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Link to original content: https://www.probes-drugs.org/compound/PD010040
AMPICILLIN (PD010040, AVKUERGKIZMTKX-NJBDSQKTSA-N)
General
Preferred name
AMPICILLIN
Synonyms
AMPICILLIN SODIUM ()
D-(-)-¦Á-Aminobenzylpenicillin ()
D-(-)-??-Aminobenzylpenicillin sodium salt ()
Domicillin ()
Citteral ()
Penialmen ()
NCI-C56086 ()
AMPICILLIN TRIHYDRATE ()
Ampicillin acid ()
D-(-)-??-Aminobenzylpenicillin ()
D-(-)-¦Á-Aminobenzylpenicillin (trihydrate) ()
D-(-)-α-Aminobenzylpenicillin (sodium salt) ()
D-(-)-α-Aminobenzylpenicillin (trihydrate) ()
D-(-)-α-Aminobenzylpenicillin ()
Ampicillin (sodium) ()
Ampicillin (trihydrate) ()
D-(-)-¦Á-Aminobenzylpenicillin sodium salt ()
NCI-C56086,D-(-)-¦Á-Aminobenzylpenicillin trihydrate ()
Ampicillin (sodium salt) ()
Ampicillin (hydrate) ()
Amp Equine ()
Polycillin-N ()
Ampicillin sodium, sterile ()
Ampicillin (as sodium) ()
Omnipen-N ()
Ampicillin sodium salt ()
NSC-755864 ()
Totacillin-N ()
Penbritin-S ()
Principen-N ()
Ampicillinum natricum ()
Ampicillin/ampicillin monohydrate ()
Ampicillin/Ampicillin Trihydrate ()
BRL-1341 ()
Ampicillin trihydrate ()
Amcill ()
Ampicillin, anhydrous ()
NSC-528986 ()
Ampicillin hydrate ()
Probampacin ()
Principen '500' ()
Ampicillin (anhydrous) ()
Tokiocillin ()
Principen '125' ()
Totacillin ()
Principen '250' ()
Ampicillin anhydrous ()
Vidopen ()
Aminobenzylpenicillin trihydrate ()
Ultrabion ()
Penbritin ()
Amfipen ()
Britcin ()
Ampicillinum ()
Alpha-Aminobenzylpenicillin ()
Redicilin ()
Principen ()
Polycillin-Prb ()
Aminobenzylpenicillin ()
Omnipen (ampicillin) ()
P-50 ()
Ampilar ()
Pfizerpen-A ()
Anhydrous ampicillin ()
WY 5103 ()
Semicillin ()
AY-6108 ()
Polycillin ()
Poly-cillin ()
P&D ID
PD010040
CAS
69-52-3
69-53-4
7177-48-2
33604-21-6
Tags
available
covalent binder
natural product
drug
Approved by
FDA
First approval
1965
1971
Drug indication
Antibacterial
Bacterial infection
Drug Status
vet_approved
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin class antibacterial. It is resistant to hydrolysis by a variety of β-lactamases, so can be to treat a diverse range of infections caused by Gram-positive and Gram-negative infections. (GtoPdb)
DESCRIPTION Ampicillin is a beta-lactam antibiotic that is a part of the aminopenicillin family. It is mainly used for infections and sepsis of the lungs, intestines, biliary tract, urinary tract caused by sensitive bacteria. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
10
Compound Sets
22
BOC Sciences Bioactive Compounds
ampicillin-sodium-cas-69-52-3-75390
Cayman Chemical Bioactives
14417
35740
ChEMBL Approved Drugs
CHEMBL1200758
CHEMBL174
ChEMBL Drugs
CHEMBL1200758
CHEMBL174
CovBinderInPDB
CBR001252
CBR001850
CBR001851
CBR001852
CBR001853
CBR003138
CBR003816
CBR004350
CBR004351
CBR005532
CBR006257
CBR006802
CBR007259
CBR007260
CBR007473
Drug Repurposing Hub
DrugBank
DB00415
DrugBank Approved Drugs
DB00415
DrugCentral
198
DrugCentral Approved Drugs
198
DrugMAP
DMHWE7P
DrugMAP Approved Drugs
DMHWE7P
Enamine BioReference Compounds
Guide to Pharmacology
10896
MedChem Express Bioactive Compound Library
HY-B0522A
HY-B0522
HY-B0522B
NCATS Inxight Approved Drugs
7C782967RD
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
ampicillin-sodium
ampicillin-trihydrate
ampicillin
TargetMol Bioactive Compound Library
T6386
T0814
The Spectrum Collection
External IDs
94
Properties
(calculated by RDKit )
Molecular Weight
349.11
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
1
cLogP
0.32
TPSA
112.73
Fraction CSP3
0.44
Chiral centers
4.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
??-Lactamase
antibiotic
Bacterial
Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell
Antibiotics,Antibiotics for Mammalian Cell Culture,Bacterial
Antibacterial
Indication
respiratory tract infections, meningitis, bacterial septicemia, endocarditis, urinary tract infections, gastrointestinal infections
MOA
bacterial cell wall synthesis inhibitor
Therapeutic Class
Antibiotics
Solubility
Slightly soluble in Aqueous Acid, DMSO
Freely soluble in water
Sparingly soluble in acetone
Source data