In 1952, Wayne Moore was a member of the team from Yale that set a world record in the 4×200 free relay. While at Yale, where he studied economics, Moore won two individual NCAA individual titles and was a two-time winner at the AAU outdoor championships. Among his other successes were a silver in the 400 freestyle and a gold in the 4×200 freestyle relay at the 1955 Pan American Games. At the 1952 Olympics, Moore placed sixth in the 400 free in addition to his gold in the relay.
Moore later became President and CEO of Moore Special Tool Company in Bridgeport, Connecticut, a company started by his father. He authored the book Foundations of Mechanical Accuracy, a text on precision engineering that became the classic reference on the subject. He also became chairman of the National Machine Tool Builder’s Association, the ACME United Corporation, and was a director for the American Precision Museum and the Bridgeport Engineering Institute.