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Select item 680061511.

A purine nucleoside that has guanine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (From Dorland, 28th ed)

Year introduced: 1972

Select item 680162442.

Guanosine 5'-O-(3-Thiotriphosphate)

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.

Year introduced: 1991

Select item 680061603.

Guanosine Triphosphate

Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.

Year introduced: 1972

Select item 680061594.

Guanosine Tetraphosphate

Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.

Year introduced: 1991(1978)

Select item 680061585.

Guanosine Pentaphosphate

Guanosine 5'-triphosphate 2'(3')-diphosphate. A guanine nucleotide containing five phosphate groups. Three phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis.

Year introduced: 1991(1978)

Select item 680061576.

Guanosine Monophosphate

A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.

Year introduced: 2012 (1994)

Select item 680061567.

Guanosine Diphosphate Sugars

Esters formed between the aldehydic carbon of sugars and the terminal phosphate of guanosine diphosphate.

Year introduced: 1991(1975)

Select item 680061558.

Guanosine Diphosphate Mannose

A nucleoside diphosphate sugar which can be converted to the deoxy sugar GDPfucose, which provides fucose for lipopolysaccharides of bacterial cell walls. Also acts as mannose donor for glycolipid synthesis.

Year introduced: 1991(1975)

Select item 680061549.

Guanosine Diphosphate Fucose

A nucleoside diphosphate sugar formed from GDPmannose, which provides fucose for lipopolysaccharides of bacterial cell walls, and for blood group substances and other glycoproteins.

Year introduced: 1991(1975)

Select item 6800615310.

Guanosine Diphosphate

A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.

Year introduced: 1991(1978)

Select item 6805089911.

GMP Reductase

An enzyme that catalyzes the reversible oxidation of inosine 5'-phosphate (IMP) to guanosine 5'-phosphate (GMP) in the presence of AMMONIA and NADP+. This enzyme was formerly classified as EC 1.6.6.8.

Year introduced: 2006(1980) use GUANOSINE MONOPHOSPHATE 1976-1979 & GUANINE NUCLEOTIDES 1976-1978

Select item 6800615212.

Cyclic GMP

Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

Year introduced: 1994

Select item 6801786913.

Cyclic GMP-Dependent Protein Kinases

A group of cyclic GMP-dependent enzymes that catalyze the phosphorylation of SERINE or THREONINE residues of proteins.

Year introduced: 1994

Select item 6709030014.

diamminechloro(guanosine-N(7))platinum(II) [Supplementary Concept]

structure in first source; RN given for (SP-4-3)-isomer

Date introduced: December 5, 1994

Select item 6800399515.

Dibutyryl Cyclic GMP

N-(1-Oxobutyl)-cyclic 3',5'-(hydrogen phosphate)-2'-butanoate guanosine. A derivative of cyclic GMP. It has a higher resistance to extracellular and intracellular phosphodiesterase than cyclic GMP.

Year introduced: 1991(1978)

Select item 6710008516.

guanosine diphosphate glucose [Supplementary Concept]

acts as a source of glucose for cellulose synthesis in some plants; minor descriptor (75-83); on-line & Index Medicus search GUANOSINE DIPHOSPHATE SUGARS (75-83); RN given refers to (alpha-D)-isomer

Date introduced: August 9, 1983

Select item 6709405917.

cisplatin-deoxy(guanosine monophosphate guanosine) adduct [Supplementary Concept]

Date introduced: July 11, 1995

Select item 6702319618.

tRNA (guanine(10)-N(2))-dimethyltransferase [Supplementary Concept]

Date introduced: January 1, 1974

Select item 6805152819.

Guanylate Kinases

Catalyzes the ATP-dependent PHOSPHORYLATION of GMP to generate GDP and ADP.

Year introduced: 2006(1980)

Select item 6802055820.