CHEBI:51066 - dapiprazole

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ChEBI Name dapiprazole
ChEBI ID CHEBI:51066
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H27N5
Net Charge 0
Average Mass 325.45138
Monoisotopic Mass 325.22665
InChI InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3
InChIKey RFWZESUMWJKKRN-UHFFFAOYSA-N
SMILES Cc1ccccc1N1CCN(CC1)CCc1nnc2CCCCn12
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
miotic
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
Application(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
miotic
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
ophthalmology drug
Any compound used for the treatment of eye conditions or eye diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dapiprazole (CHEBI:51066) has role α-adrenergic antagonist (CHEBI:37890)
dapiprazole (CHEBI:51066) has role antipsychotic agent (CHEBI:35476)
dapiprazole (CHEBI:51066) has role miotic (CHEBI:51068)
dapiprazole (CHEBI:51066) has role ophthalmology drug (CHEBI:66981)
dapiprazole (CHEBI:51066) is a N-alkylpiperazine (CHEBI:46845)
dapiprazole (CHEBI:51066) is a N-arylpiperazine (CHEBI:46848)
dapiprazole (CHEBI:51066) is a pyridines (CHEBI:26421)
IUPAC Name
3-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine
INNs Sources
dapiprazol WHO MedNet
dapiprazole WHO MedNet
dapiprazole ChemIDplus
dapiprazolum WHO MedNet
Synonym Source
5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine ChemIDplus
Manual Xrefs Databases
781 DrugCentral
D07775 KEGG DRUG
Dapiprazole Wikipedia
DB00298 DrugBank
DE2915318 Patent
US4252721 Patent
View more database links
Registry Numbers Types Sources
72822-12-9 CAS Registry Number ChemIDplus
839674 Beilstein Registry Number Beilstein
Last Modified
22 February 2017