Abstract
Early-stage breast cancer detection remains a critical challenge in healthcare, demanding innovative approaches that leverage the power of deep learning and transfer learning techniques. The problem to be investigated involves designing a model capable of extracting meaningful features from mammographic images, maximizing transferability across datasets, and optimizing the trade-off between model complexity and computational efficiency. Existing methods often face limitations in achieving high accuracy, robustness, and efficiency. This research aims to address these challenges by proposing a novel transfer learning approach that combines the strengths of VGG11 and EfficientNet architectures for early-stage breast cancer detection. In the case of technological development, there is never a shortage of opportunities in the field of medical imaging. Cancer patients who have an earlier diagnosis of their disease have a lower probability of passing away from their illness. This research proposed an novel early neural network based on transfer learning names as ‘EARLYNET’ to automate breast cancer prediction. In this research, the new hybrid deep learning model was devised and built for distinguishing benign breast tumors from malignant ones. The trials were carried out on the Breast Histopathology Image dataset, and the model was evaluated using a Mobile net founded on the transfer learning method. In terms of accuracy, this model delivers 91.53% accuracy. Explored how the proposed transfer learning framework can enhance the accuracy and reliability of early-stage breast cancer detection, contributing to advancements in medical image analysis and positively impacting patient outcomes.
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References
Abunasser BS, Rasheed AL-Hiealy MRJ, Zaqout IS, Abu-Naser SS (2022) Breast cancer detection and classification using deep learning Xception algorithm. Int J Adv Comput Sci Appl. https://doi.org/10.14569/IJACSA.2022.0130729
Abunasser BS, Rasheed AL-Hiealy MRJ, Zaqout IS, Abu-Naser SS (2023) Convolution neural network for breast cancer detection and classification using deep learning. Asian Pac J Cancer Prev 24(2):531–544. https://doi.org/10.31557/APJCP.2023.24.2.531
Ahmad DR, Rasool M, Assad A (2022) Breast cancer detection using deep learning: datasets, methods, and challenges ahead. Comput Biol Med 149:106073
Arya N, Saha S (2020) Multi-modal classification for human breast cancer prognosis prediction: proposal of deep-learning based stacked ensemble model. IEEE/ACM Trans Comput Biol Bioinf. https://doi.org/10.1109/TCBB.2020.3018467
Chen X-W, Lin X (2014) Big data deep learning: challenges and perspectives. IEEE Access 2:514–525
Cireşan DC, Giusti A, Gambardella LM, Schmidhuber J (2013) Mitosis detection in breast cancer histology images with deep neural networks. In: Paper presented at the International conference on medical image computing and computer-assisted intervention
Cruz-Roa A, Basavanhally A, González F, Gilmore H, Feldman M, Ganesan S, Madabhushi A (2014) Automatic detection of invasive ductal carcinoma in whole slide images with convolutional neural networks. In: Paper presented at the medical imaging 2014: digital pathology
Deng J, Russakovsky O, Krause J, Bernstein MS, Berg A, Fei-Fei L (2014) Scalable multi-label annotation. In: Paper presented at the proceedings of the SIGCHI conference on human factors in computing systems
DeSantis C, Siegel R, Bandi P, Jemal A (2011) Breast cancer statistics, 2011. CA A Cancer J Clinicians 61(6):408–418. https://doi.org/10.3322/caac.20134
Dhungel N, Carneiro G, Bradley AP (2015) Automated mass detection in mammograms using cascaded deep learning and random forests. In: Paper presented at the 2015 international conference on digital image computing: techniques and applications (DICTA)
Dora L, Agrawal S, Panda R, Abraham A (2017) Optimal breast cancer classification using Gauss–Newton representation based algorithm. Expert Syst Appl 85:134–145. https://doi.org/10.1016/j.eswa.2017.05.035
Elston CW, Ellis IO (1991) Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19(5):403–410
Ganesan K, Acharya UR, Chua CK, Min LC, Abraham KT, Ng K-H (2012) Computer-aided breast cancer detection using mammograms: a review. IEEE Rev Biomed Eng 6:77–98
Genestie C, Zafrani B, Asselain B, Fourquet A, Rozan S, Validire P, Sastre-Garau X (1998) Comparison of the prognostic value of Scarff-Bloom-Richardson and Nottingham histological grades in a series of 825 cases of breast cancer: major importance of the mitotic count as a component of both grading systems. Anticancer Res 18(1B):571–576
He K, Zhang X, Ren S, Sun J (2015) Delving deep into rectifiers: Surpassing human-level performance on imagenet classification. In: Paper presented at the Proceedings of the IEEE international conference on computer vision
He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: Paper presented at the Proceedings of the IEEE conference on computer vision and pattern recognition
Ioffe S, Szegedy C (2015) Batch normalization: accelerating deep network training by reducing internal covariate shift. In: Paper presented at the international conference on machine learning
Janowczyk A, Madabhushi A (2016) Deep learning for digital pathology image analysis: a comprehensive tutorial with selected use cases. J Pathol Inf 7(1):29
Krizhevsky A, Sutskever I, Hinton GE (2012) Imagenet classification with deep convolutional neural networks. Part of Advances in Neural Information Processing Systems 25 (NIPS 2012)
Kumar M, Singhal S, Shekhar S, Sharma B, Srivastava G (2022) Optimized stacking ensemble learning model for breast cancer detection and classification using machine learning. Sustainability 14(21):13998
Malebary SJ, Hashmi A (2021) Automated breast mass classification system using deep learning and ensemble learning in digital mammogram. IEEE Access 9:55312–55328
Malvia S, Bagadi SA, Dubey US, Saxena S (2017) Epidemiology of breast cancer in Indian women. Asia-Pac J Clin Oncol 13(4):289–295
MohsinJadoon M, Zhang Q, Haq IUl, Butt S, Jadoon A (2017) Three-class mammogram classification based on descriptive CNN features. BioMed Res Int 2017:1–11. https://doi.org/10.1155/2017/3640901
New York State Department of Environmental Conservation (2009) Guidelines for conducting bird and bat studies at commercial wind energy projects. Albany, NY Retrieved from http://www.dec.ny.gov/docs/wildlife_pdf/windguidelines.pdf
Pandian AP (2019) Identification and classification of cancer cells using capsule network with pathological images. J Artif Intell 1(01):37–44
Pereira DC, Ramos RP, Do Nascimento MZ (2014) Segmentation and detection of breast cancer in mammograms combining wavelet analysis and genetic algorithm. Comput Methods Programs Biomed 114(1):88–101
Prakash SS, Visakha K (2020) Breast cancer malignancy prediction using deep learning neural networks. In: Paper presented at the 2020 second international conference on inventive research in computing applications (ICIRCA)
Ren S, Sun J, He K, Zhang X (2016) Deep residual learning for image recognition. In: Paper presented at the CVPR
Romero FP, Tang A, Kadoury S (2019) Multi-level batch normalization in deep networks for invasive ductal carcinoma cell discrimination in histopathology images. In: 2019 IEEE 16th international symposium on biomedical imaging (ISBI 2019) pp 1092–1095. IEEE
Saeed Khodary M, Hamouda RH, El Ezz A, Wahed ME (2017) Enhancement accuracy of breast tumor diagnosis in digital mammograms. J Biomed Sci. https://doi.org/10.4172/2254-609X.100072
Seedat N, Aharonson V (2021) Machine learning discrimination of Parkinson’s disease stages from walker-mounted sensors data. In: Shaban-Nejad A, Michalowski M, Buckeridge DL (eds) Explainable AI in Healthcare and Medicine: Building a Culture of Transparency and Accountability. Springer International Publishing, Cham, pp 37–44. https://doi.org/10.1007/978-3-030-53352-6_4
Sermanet P, Eigen D, Zhang X, Mathieu M, Fergus R, LeCun Y (2014) D.: overfeat: integrated recognition, localization and detection using convolutional networks arXiv. In: Paper presented at the 1312. 6229v3 [cs. CV] 14
Shastri AA, Tamrakar D, Ahuja K (2018) Density-wise two stage mammogram classification using texture exploiting descriptors. Expert Syst Appl 99:71–82. https://doi.org/10.1016/j.eswa.2018.01.024
Shi P, Wu C, Zhong J, Wang H (2019) Deep learning from small dataset for BI-RADS density classification of mammography images. In: Paper presented at the 2019 10th international conference on information technology in medicine and education (ITME)
Szegedy C, Liu W, Jia Y, Sermanet P, Reed S, Anguelov D, Rabinovich A (2015) Going deeper with convolutions. In: Proceedings of the IEEE conference on computer vision and pattern recognition
Tan M, Le Q (2019) Efficientnet: rethinking model scaling for convolutional neural networks
Tzikopoulos SD, Mavroforakis ME, Georgiou HV, Dimitropoulos N, Theodoridis SJ (2011) A fully automated scheme for mammographic segmentation and classification based on breast density and asymmetry. Comput Methods Programs Biomed 102(1):47–63
Xiang Z, Ting Z, Weiyan F, Cong L (2019) Breast cancer diagnosis from histopathological image based on deep learning. In: Paper presented at the 2019 Chinese Control and Decision Conference (CCDC)
Xie W, Li Y, Ma YJN (2016) Breast mass classification in digital mammography based on extreme learning machine. Neurocomputing 173:930–941
Zeiler MD, Fergus R (2014) Visualizing and understanding convolutional networks. In: Paper presented at the European conference on computer vision
Zhang X, He D, Zheng Y, Huo H, Li S, Chai R, Liu TJIA (2020) Deep learning-based analysis of breast cancer using advanced ensemble classifier and linear discriminant analysis. IEEE Access 8:120208–120217
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Souza, M.D., Prabhu, G.A., Kumara, V. et al. EarlyNet: a novel transfer learning approach with VGG11 and EfficientNet for early-stage breast cancer detection. Int J Syst Assur Eng Manag 15, 4018–4031 (2024). https://doi.org/10.1007/s13198-024-02408-6
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DOI: https://doi.org/10.1007/s13198-024-02408-6