Change Accessibility Display preferences on Mac
On your Mac, use the Display pane of Accessibility System Preferences to make items on the screen easier to see and read, and to reduce motion on the screen.
To change these preferences, choose Apple menu 
> System Preferences, click Accessibility, then click Display.
Invert colors | Invert the colors on your display. For example, text appears in white on a black background. If you turn on Night Shift, “Invert colors” is automatically disabled. |
Use grayscale | Remove colors from the screen. |
Differentiate without color | Use shapes, in addition to or instead of color, to convey status or information. |
Reduce motion | Stop or reduce the movement of elements on the screen—for example, when you open apps, switch between desktops, or open and close Notification Center. |
Increase contrast | Increase the contrast of items on the screen (such as borders around buttons or boxes) without changing the contrast of the screen itself. |
Reduce transparency | Replace the transparent effect used on some backgrounds in macOS with a darker background, to improve contrast and readability. |
Display contrast | Increase the screen contrast. |
Cursor size | Increase the size of the pointer. |
Shake mouse pointer to locate | Quickly move your finger on the trackpad or quickly move the mouse to temporarily enlarge the pointer so you can find it. |
To quickly turn “Invert colors” on or off using the Accessibility Options shortcut panel, press Option-Command-F5 (or if your Mac has Touch ID, quickly press Touch ID three times).
You can enable keyboard shortcuts for inverting colors and changing the contrast in the Accessibility section of the Shortcuts pane of Keyboard preferences. To open the pane, choose Apple menu > System Preferences, click Keyboard, then click Shortcuts.