Isolation and identification of alpha-glucosidase inhibitors from tochu-cha (Eucommia ulmoides)
- PMID: 9028049
- DOI: 10.1271/bbb.61.177
Isolation and identification of alpha-glucosidase inhibitors from tochu-cha (Eucommia ulmoides)
Abstract
alpha-Glucosidase inhibitory activity was found in aqueous methanol extracts of tochu-cha, dried leaves of Eucommia ulmoides (Eucommiaceae). Five active principles against yeast enzyme were isolated and characterized. Among them, quercetin (1, Ki: 8.5 x 10(-6) M) was considered to contribute mostly to the activity of the tochu leaves. In regard to an animal alpha-glucosidase, rat intestinal sucrase activity was also inhibited by 1.
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