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Link to original content: https://pubmed.ncbi.nlm.nih.gov/8824806
Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q - PubMed Skip to main page content
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. 1996 Jan 15;31(2):230-3.
doi: 10.1006/geno.1996.0036.

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q

S W Scherer  1 , R M Duvoisin, R Kuhn, H H Heng, E Belloni, L C Tsui
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Free article

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q

S W Scherer et al. Genomics. .
Free article

Abstract

Metabotropic glutamate receptors (GRMs) are neurotransmitter receptors that respond to glutamate stimulations by activating GTP-binding proteins and modulating second-messenger cascades. Eight related GRMs have been identified to date. In this study, we have mapped GRM3 and GRM8 to human chromosome 7q21.1-q21.2 and 7q31.3-q32.1, respectively, using somatic cell hybrid and fluorescence in situ hybridization analysis. A yeast artificial chromosome contig was constructed surrounding the genes, allowing their location to be integrated into the genetic and physical map of chromosome 7.

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