iBet uBet web content aggregator. Adding the entire web to your favor.
iBet uBet web content aggregator. Adding the entire web to your favor.



Link to original content: https://pubmed.ncbi.nlm.nih.gov/37962057
Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies - PubMed Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023;63(29):9926-9936.
doi: 10.1080/10408398.2022.2075311. Epub 2022 May 16.

Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies

Eliška Selinger  1   2   3 , Manuela Neuenschwander  4   5 , Alina Koller  6   7 , Jan Gojda  1   3 , Tilman Kühn  7   8   9 , Lukas Schwingshackl  10 , Janett Barbaresko  4 , Sabrina Schlesinger  4   5
Affiliations

Evidence of a vegan diet for health benefits and risks - an umbrella review of meta-analyses of observational and clinical studies

Eliška Selinger et al. Crit Rev Food Sci Nutr. 2023.

Abstract

To summarize and evaluate the evidence on the health impact of a vegan diet, we conducted an umbrella review of systematic reviews and meta-analyses. PubMed, Cochrane Library, Web of Science and Epistemonikos were searched up to September 2021. Meta-analyses were recalculated by using a random effects model. The certainty of evidence (CoE) was evaluated by the GRADE approach. For the general healthy population, a vegan diet was effective for reducing body weight [MD (95% CI): -2.52 kg (-3.06, -1.98), n = 8 RCTs; moderate CoE] and was associated with further health benefits (with low CoE), including a lower risk of cancer incidence [SRR (95% CI): 0.84 (0.75, 0.95), n = 2] and a trend for lower risk of all-cause mortality [SRR (95% CI): 0.87 (0.75, 1.01), n = 2], as well as lower ApoB levels [MD (95% CI): -0.19 µmol/L (-0.23, -0.15), n = 7 RCTs). The findings suggested adverse associations for a vegan diet with risk of fractures [SRR (95% CI): 1.46 (1.03, 2.07), n = 3; low CoE]. For persons with diabetes or at high CVD risk, a vegan diet reduced measures of adiposity, total cholesterol, LDL and improved glycemic control (CoE moderate to low). A vegan diet may have the potential for the prevention of cardiometabolic health, but it may also impair bone health. More well-conducted primary studies are warranted.

Keywords: Health; meta-analysis; plant-based; systematic review; umbrella review; vegan diet.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources