Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study
- PMID: 32991045
- DOI: 10.1111/jocd.13739
Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study
Abstract
Background: Trichoscopy is a useful tool for diagnosis and follow-up of alopecia areata (AA) patients. Both platelet-rich plasma (PRP) and intralesional corticosteroids (ILCs) are important treatment modalities of patchy AA.
Aim: Trichoscopic diagnosis of AA and monitoring the treatment response to PRP versus ILCs in patchy AA treatment.
Patients/methods: This comparative study included 31 patients with patchy AA, divided into two groups: (group A) received ILCs while (group B) received PRP once monthly for 3 months. Evaluation was done by Severity of Alopecia Tool (SALT) score, Alopecia Areata Symptom Impact Scale (AASIS), photography, and dermoscopy.
Results: There was a significant improvement in trichoscopic findings in both groups with regard to the number of follicular units per opening, black dots, broken hairs, and dystrophic changes. Final SALT score showed significant lower levels in both groups compared to baseline levels (P = .025 & P = .008). Final AASIS showed significant decrease in group B (P = .006) not in group A (P = .062).
Conclusion: Trichoscopy can help in the diagnosis, evaluation of the efficacy and safety of both modalities and might give a clue for treatment response. Both ILCs and PRP were effective in patchy AA treatment.
Keywords: Alopecia areata; SALT score; dermoscopy; intralesional corticosteroids; platelet-rich plasma.
© 2020 Wiley Periodicals LLC.
Similar articles
-
Trichoscopy pattern in alopecia areata: A systematic review and meta-analysis.Skin Res Technol. 2023 Jun;29(6):e13378. doi: 10.1111/srt.13378. Skin Res Technol. 2023. PMID: 37357664 Free PMC article. Review.
-
Platelets rich plasma versus minoxidil 5% in treatment of alopecia areata: A trichoscopic evaluation.Dermatol Ther. 2017 Jan;30(1). doi: 10.1111/dth.12437. Epub 2016 Oct 28. Dermatol Ther. 2017. PMID: 27791311 Clinical Trial.
-
Alopecia areata predictive score: A new trichoscopy-based tool to predict treatment outcome in patients with patchy alopecia areata.J Cosmet Dermatol. 2020 Mar;19(3):746-751. doi: 10.1111/jocd.13064. Epub 2019 Jul 13. J Cosmet Dermatol. 2020. PMID: 31301100
-
Use of trichoscopy for the diagnosis of alopecia areata coexisting with primary scarring alopecia in a female hair loss patient.J Dermatol. 2019 May;46(5):418-421. doi: 10.1111/1346-8138.14841. Epub 2019 Mar 7. J Dermatol. 2019. PMID: 30843255
-
Trichoscopy of alopecia areata: An update.J Dermatol. 2018 Jun;45(6):692-700. doi: 10.1111/1346-8138.14283. Epub 2018 Mar 22. J Dermatol. 2018. PMID: 29569271 Review.
Cited by
-
Non-Invasive Techniques for Evaluating Alopecia Areata.Maedica (Bucur). 2023 Jun;18(2):333-341. doi: 10.26574/maedica.2023.18.2.333. Maedica (Bucur). 2023. PMID: 37588838 Free PMC article.
-
Trichoscopy pattern in alopecia areata: A systematic review and meta-analysis.Skin Res Technol. 2023 Jun;29(6):e13378. doi: 10.1111/srt.13378. Skin Res Technol. 2023. PMID: 37357664 Free PMC article. Review.
-
Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study.Arch Dermatol Res. 2023 Aug;315(6):1675-1688. doi: 10.1007/s00403-023-02565-x. Epub 2023 Feb 21. Arch Dermatol Res. 2023. PMID: 36809409 Free PMC article.
-
Platelet-rich plasma in alopecia areata and primary cicatricial alopecias: A systematic review.Front Med (Lausanne). 2022 Nov 24;9:1058431. doi: 10.3389/fmed.2022.1058431. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36507528 Free PMC article.
-
Platelet-Rich Plasma in Alopecia Areata-A Steroid-Free Treatment Modality: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Biomedicines. 2022 Jul 29;10(8):1829. doi: 10.3390/biomedicines10081829. Biomedicines. 2022. PMID: 36009377 Free PMC article. Review.
References
REFERENCES
-
- Villasante Fricke AC, Miteva M. Epidemiology and burden of alopecia areata: a systematic review. Clin Cosmet Investig Dermatol. 2015;24(8):397-403.
-
- Wang ECE, Christiano AM. The changing landscape of alopecia Areata: the translational landscape. Adv Ther. 2017;34(7):1586-1593.
-
- Meah N, Wall D, York K, et al. The Alopecia Areata Consensus of Experts (ACE) study: results of an international expert opinion on treatments for alopecia areata. J Am Acad Dermatol. 2020;83(1):123-130.
-
- Lacarrubba F, Dall'Oglio F, Rita Nasca M, Micali G. Videodermatoscopy enhances diagnostic capability in some forms of hair loss. Am J Clin Dermatol. 2004;5(3):205-208.
-
- Waśkiel A, Rakowska A, Sikora M, Olszewska M, Rudnicka L. Trichoscopy of alopecia areata: an update. J Dermatol. 2018;45(6):692-700.
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials