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Streptococcus Pyogenes

Sidrah Kanwal  1 , Pradeep Vaitla  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
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Book

Streptococcus Pyogenes

Sidrah Kanwal et al.
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Excerpt

Streptococcus pyogenes is a major human-specific bacterial pathogen that causes a wide array of manifestations ranging from mild localized infections to life-threatening invasive infections. Ineffective treatment of S. pyogenes infections can result in the postinfectious sequela acute rheumatic fever and post-streptococcal glomerulonephritis. Moreover, it causes invasive infections like necrotizing fasciitis and toxic shock syndrome that is associated with and high morbidity and mortality.

Streptococci are gram-positive, catalase-negative, coagulase-negative cocci that occur in pairs or chains. They are divided into three groups by the type of hemolysis on blood agar: beta-hemolytic (complete lysis of red cells), a hemolytic (green hemolysis), and gamma-hemolytic (no hemolysis). Beta-hemolytic streptococci are characterized as group A streptococci (Streptococcus pyogenes) and group B streptococci (Streptococcus agalactiae).

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Conflict of interest statement

Disclosure: Sidrah Kanwal declares no relevant financial relationships with ineligible companies.

Disclosure: Pradeep Vaitla declares no relevant financial relationships with ineligible companies.

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