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Link to original content: https://pubmed.ncbi.nlm.nih.gov/2898107
Anorexia in the elderly - PubMed Skip to main page content
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Review
. 1988 Jan-Feb;9(1):9-16.
doi: 10.1016/s0197-4580(88)80004-6.

Anorexia in the elderly

J E Morley  1 , A J Silver
Affiliations
Review

Anorexia in the elderly

J E Morley et al. Neurobiol Aging. 1988 Jan-Feb.

Abstract

Weight loss and anorexia occur commonly in the elderly. While in many cases the anorexia can be attributed to associated disease processes, it does appear that a true anorexia of aging exists. Animal studies have suggested that older rodents have an excessive satiety effect of cholecystokinin and a decreased opioid feeding drive. Other older persons develop anorexia in association with depression. In these subjects, excess corticotropin-releasing factor may be the neurotransmitter involved in the pathogenesis of the anorexia. In Alzheimer's disease, decreases in norepinephrine and neuropeptide Y may be involved in the anorexia seen in the these patients.

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