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Link to original content: https://pubmed.ncbi.nlm.nih.gov/26668136
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Review
. 2016 Apr;10(2):130-5.
doi: 10.1177/1753465815621233. Epub 2015 Dec 14.

Is there a role for e-cigarettes in smoking cessation?

Charlotte Leduc  1 , Elisabeth Quoix  2
Affiliations
Review

Is there a role for e-cigarettes in smoking cessation?

Charlotte Leduc et al. Ther Adv Respir Dis. 2016 Apr.

Abstract

The use of e-cigarettes has dramatically increased over the past few years and their role in smoking cessation remains controversial. Several clinical studies have evaluated their efficacy in smoking cessation but most of them are prospective cohort studies. Only two randomized, controlled trials have compared e-cigarettes versus placebo or patches. A meta-analysis of these two randomized, controlled trials has been performed. Nicotine-containing e-cigarettes appear to help smokers unable to stop smoking altogether to reduce their cigarette consumption when compared with placebo. However, these results are rated 'low' by GRADE standards. Many cohort studies have been conducted, with contradictory results. For some, e-cigarettes could increase the risk of nonsmokers developing nicotine dependence and of current smokers maintaining their dependence. The debate remains open and more randomized trials are needed with long-term data about the efficacy and safety of e-cigarettes.

Keywords: e-cigarette; nicotine replacement therapy; smoking cessation.

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Conflict of interest statement

Conflict of interest statement: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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