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Link to original content: https://pubmed.ncbi.nlm.nih.gov/25132976
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Review
. 2014 Aug;6(8):1097-104.
doi: 10.3978/j.issn.2072-1439.2014.03.23.

Donor selection in heart transplantation

Ahmet Kilic  1 , Sitaramesh Emani  1 , Chittoor B Sai-Sudhakar  1 , Robert S D Higgins  1 , Bryan A Whitson  1
Affiliations
Review

Donor selection in heart transplantation

Ahmet Kilic et al. J Thorac Dis. 2014 Aug.

Abstract

There is increased scrutiny on the quality in health care with particular emphasis on institutional heart transplant survival outcomes. An important aspect of successful transplantation is appropriate donor selection. We review the current guidelines as well as areas of controversy in the selection of appropriate hearts as donor organs to ensure optimal outcomes. This decision is paramount to the success of a transplant program as well as recipient survival and graft function post-transplant.

Keywords: Heart transplant; donor selection.

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Figures

Figure 1
Figure 1
The perfect situation for transplantation would be an ideal donor organ (+) being transplanted into an ideal recipient (+) with minimal co-morbidities and expected great outcomes. In contrast, a marginal donor organ (–) should not be used in recipient with multiple co-morbidities (–).The gray area in transplantation occurs when there is a mismatch between either an ideal donor (+) and non-ideal recipient (–) or vice versa with a non-ideal donor (–) with an ideal, relatively healthy recipient (+). An understanding of the following concepts are mandatory to provide the framework for acceptance of donor hearts and to provide the best organ-recipient matching to provide optimal outcomes.
Figure 2
Figure 2
The Crystal City Guidelines for an algorithm for the management of potential heart donors (19). CVP, central venous pressure; HCT, hematocrit; Hgb, hemoglobin; MAP, mean arterial pressure; LVEF, left ventricular ejection fraction; T3, triiodothyronine; SVR, systemic vascular resistance; BG, blood glucose; PCWP, pulmonary capillary wedge pressure.
See this image and copyright information in PMC

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