iBet uBet web content aggregator. Adding the entire web to your favor.
iBet uBet web content aggregator. Adding the entire web to your favor.



Link to original content: https://pubmed.ncbi.nlm.nih.gov/20460470/
VISIBIOweb: visualization and layout services for BioPAX pathway models - PubMed Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jul;38(Web Server issue):W150-4.
doi: 10.1093/nar/gkq352. Epub 2010 May 11.

VISIBIOweb: visualization and layout services for BioPAX pathway models

Affiliations

VISIBIOweb: visualization and layout services for BioPAX pathway models

Alptug Dilek et al. Nucleic Acids Res. 2010 Jul.

Abstract

With recent advancements in techniques for cellular data acquisition, information on cellular processes has been increasing at a dramatic rate. Visualization is critical to analyzing and interpreting complex information; representing cellular processes or pathways is no exception. VISIBIOweb is a free, open-source, web-based pathway visualization and layout service for pathway models in BioPAX format. With VISIBIOweb, one can obtain well-laid-out views of pathway models using the standard notation of the Systems Biology Graphical Notation (SBGN), and can embed such views within one's web pages as desired. Pathway views may be navigated using zoom and scroll tools; pathway object properties, including any external database references available in the data, may be inspected interactively. The automatic layout component of VISIBIOweb may also be accessed programmatically from other tools using Hypertext Transfer Protocol (HTTP). The web site is free and open to all users and there is no login requirement. It is available at: http://visibioweb.patika.org.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
High-level architecture of VISIBIOweb depicted with a UML component diagram.
Figure 2.
Figure 2.
A sample screenshot from VISIBIOweb. The GUI is organized into a menu bar, a toolbar, and a canvas with various controls. An object inspection window is opened upon demand.
Figure 3.
Figure 3.
Display and layout options in load dialog.
Figure 4.
Figure 4.
A sample view of the Persist BioPAX model view dialog.
Figure 5.
Figure 5.
A sample pathway view (Cam-PDE 1 activation) and its geometry in native VISIBIOweb format (certain parts hidden for brevity).

Similar articles

Cited by

References

    1. Demir E, Babur O, Dogrusoz U, Gursoy A, Ayaz A, Gulesir G, Nisanci G, Cetin-Atalay R. An ontology for collaborative construction and analysis of cellular pathways. Bioinformatics. 2004;20:349–356. - PubMed
    1. BioPAX. [(4 May 2010, date last accessed)]. Biological pathways exchange. http://www.biopax.org.
    1. Caspi R, Foerster H, Fulcher CA, Kaipa P, Krummenacker M, Latendresse M, Paley S, Rhee SY, Shearer AG, Tissier C, et al. The MetaCyc Database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases. Nucleic Acids Res. 2008;36:D623–D631. - PMC - PubMed
    1. Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, et al. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics. 2003;19:524–531. - PubMed
    1. Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, et al. KEGG for linking genomes to life and the environment. Nucleic Acids Res. 2008;36:D480–D484. - PMC - PubMed

Publication types