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Link to original content: https://pubmed.ncbi.nlm.nih.gov/16162299
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. 2005 Sep 15:5:8.
doi: 10.1186/1472-6815-5-8.

Giant cell tumor of the temporal bone--a case report

S Balaji Pai #  1 , R M Lalitha #  2 , Kavitha Prasad  2 , Saraswathi G Rao  3 , K Harish  4
Affiliations

Giant cell tumor of the temporal bone--a case report

S Balaji Pai et al. BMC Ear Nose Throat Disord. .

Abstract

Background: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. The petrous portion of the temporal bone forms a rare location for this tumor.

Case presentation: The authors report a case of a large giant cell tumor involving the petrous and squamous portions of the temporal bone in a 26 year old male patient. He presented with right side severe hearing loss and facial paresis. Radical excision of the tumor was achieved but facial palsy could not be avoided.

Conclusion: Radical excision of skull base giant cell tumor may be hazardous but if achieved is the optimal treatment and may be curative.

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Figures

Figure 1
Figure 1
Preoperative CT scan. Preoperative axial CT scan which shows a large hyperdense tumor arising from the petrous portion of the right temporal bone with intracranial extension and impending uncal herniation.
Figure 2
Figure 2
Preoperative CT scan. The figure shows the sagittal and coronal reconstruction of the tumor.
Figure 3
Figure 3
Tumor exposure. Right temporoparietal craniectomy and tumor exposure after right external carotid artery control (inset) and excision of the temporalis muscle. Tumor was friable, reddish brown and vascular.
Figure 4
Figure 4
After completion of tumor excision. After radical excision of tumor (piecemeal) the defect is covered with gelfoam.
Figure 5
Figure 5
Microphotograph of the tumor. Microphotograph (250×) of the specimen in H & E stains showing neoplastic stromal cells and multinucleated giant cells. The stromal cells (horizontal arrow) are round to spindle shaped with moderate amount of eosinophilic cytoplasm and a single nucleus. They are mesenchymal in origin. The multinucleated giant cells (vertical arrow) are large in size with eosinophilic cytoplasm and a large number of nuclei.
Figure 6
Figure 6
Postoperative CT. Postoperative CT scan of the patient showing total excision of the tumor and the normal alignment of the intracranial structures.
See this image and copyright information in PMC

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