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Link to original content: https://pubmed.ncbi.nlm.nih.gov/11579070
Phenylethylamine, a possible link to the antidepressant effects of exercise? - PubMed Skip to main page content
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Clinical Trial
. 2001 Oct;35(5):342-3.
doi: 10.1136/bjsm.35.5.342.

Phenylethylamine, a possible link to the antidepressant effects of exercise?

A Szabo  1 , E Billett, J Turner
Affiliations
Clinical Trial

Phenylethylamine, a possible link to the antidepressant effects of exercise?

A Szabo et al. Br J Sports Med. 2001 Oct.

Abstract

Objectives: To determine in this pilot study whether aerobic exercise affects phenylacetic acid concentration in the urine.

Methods: Twenty healthy men provided 24 hour urine samples on two consecutive days for the determination of phenylacetic acid levels. Before and during day 1, subjects refrained from physical activity; on day 2 subjects ran on a treadmill at 70% of their maximal heart rate reserve (MHRR) for 30 minutes.

Results: The 24 hour mean urinary concentration of phenylacetic acid was increased by 77% after exercise.

Conclusion: As phenylacetic acid concentration in urine reflects phenylethylamine level, which is known to have antidepressant effects, phenylethylamine may be linked to the therapeutic effects of physical exercise on depression.

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References

    1. Sports Med. 1999 Nov;28(5):337-74 - PubMed
    1. Anal Biochem. 1984 Jan;136(1):202-7 - PubMed
    1. J Neuropsychiatry Clin Neurosci. 1995 Winter;7(1):6-14 - PubMed
    1. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):168-71 - PubMed

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