Historical and literary accounts of the Graaff-Reinet and Swellendam rebellions of 1795 – 1799 ar... more Historical and literary accounts of the Graaff-Reinet and Swellendam rebellions of 1795 – 1799 are analysed in relation to three consecutive myths of Afrikaner national identity. In terms of the British imperialist myth of the Afrikaner as rural degenerate, the rebels were semi-civilised burgher racists, who sought to dignify their killing and enslavement of the Khoikhoi and Xhosa by recourse
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan A... more African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11 megabase-sized chromosomes of Trypanosoma brucei . The 26-megabase genome contains 9068 predicted genes, including ∼900 pseudogenes and ∼1700 T. brucei –specific genes. Large subtelomeric arrays contain an archive of 806 variant surface glycoprotein (VSG) genes used by the parasite to evade the mammalian immune system. Most VSG genes are pseudogenes, which may be used to generate expressed mosaic genes by ectopic recombination. Comparisons of the cytoskeleton and endocytic trafficking systems with those of humans and other eukaryotic organisms reveal major differences. A comparison of metabolic pathways encoded by the genomes of T. brucei, T. cruzi , and Leishmania major reveals the least overall metabolic capability in T. brucei and the greatest in L. major . Horizontal transfer of genes of bacterial origin has contributed to some of...
Historical and literary accounts of the Graaff-Reinet and Swellendam rebellions of 1795 – 1799 ar... more Historical and literary accounts of the Graaff-Reinet and Swellendam rebellions of 1795 – 1799 are analysed in relation to three consecutive myths of Afrikaner national identity. In terms of the British imperialist myth of the Afrikaner as rural degenerate, the rebels were semi-civilised burgher racists, who sought to dignify their killing and enslavement of the Khoikhoi and Xhosa by recourse
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan A... more African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11 megabase-sized chromosomes of Trypanosoma brucei . The 26-megabase genome contains 9068 predicted genes, including ∼900 pseudogenes and ∼1700 T. brucei –specific genes. Large subtelomeric arrays contain an archive of 806 variant surface glycoprotein (VSG) genes used by the parasite to evade the mammalian immune system. Most VSG genes are pseudogenes, which may be used to generate expressed mosaic genes by ectopic recombination. Comparisons of the cytoskeleton and endocytic trafficking systems with those of humans and other eukaryotic organisms reveal major differences. A comparison of metabolic pathways encoded by the genomes of T. brucei, T. cruzi , and Leishmania major reveals the least overall metabolic capability in T. brucei and the greatest in L. major . Horizontal transfer of genes of bacterial origin has contributed to some of...
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