Abstract
IN 1946 two crystalline acidic antibiotics (‘nudic acids A and B’) were isolated from the culture medium of the basidiomycete Tricholoma nudum (Bull.) Fr. and some preliminary work on their respective constitutions was carried out1. It has now been shown that ‘nudic acid B’ is identical with ‘diatretyne II’ (7-cyano-trans-hept-2-en-4 : 6-diynoic acid (I)), which is produced by another fungus, Clitocybe diatreta 2, and which has been obtained synthetically (Ashworth, Jones, Mansfield, Schlögl, Thompson and Whiting, unpublished work).
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References
Florey, Chain, Heatley, Jennings, Sanders, Abraham and Florey, “Antibiotics”, 358, (Oxford University Press, 1949).
Anchel, Science, 121, 607 (1955).
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HEATLEY, N., STEPHENSON, J. Identity of ‘Nudic Acid B’ and ‘Diatretyne II’. Nature 179, 1078 (1957). https://doi.org/10.1038/1791078a0
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DOI: https://doi.org/10.1038/1791078a0
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