Abstract
The distribution of Y-chromosomal single nucleotide polymorphism (SNP) haplogroups and short tandem repeat (STR) haplotypes was determined in a sample of 102 unrelated men of Arab origin from northwestern Algeria (Oran area). A total of nine different haplogroups were identified by a panel of 22 binary markers. The most common haplogroups observed in the Algerian population were E3b2 (45.1%) and J1 (22.5%). Y-STR typing by a 17-loci multiplex system allowed 93 haplotypes to be defined (88 were unique). Striking differences in the allele distribution and gene diversity of Y-STR markers between haplogroups could be found. In particular, intermediate alleles at locus DYS458 specifically characterized the haplotypes of individuals carrying haplogroup J1. All the intermediate alleles shared a common repeat sequence structure, supporting the hypothesis that the variant originated from a single mutational event.
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Acknowledgements
The continuing support of the Compagnia di San Paolo to C. Torre’s laboratory is gratefully acknowledged. We also thank Dr Boudjema A, Medienne Benchekor S and Meghoufel N for assistance in the collection of the samples.
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Fig. S1
NJ tree forAlgerian Arabs “A-AR”(n = 102) and 11 reference populations: Algerian Berbers “A-B”(n = 16), northern “E-N”(n = 47) and southern Egyptians “E-S”(n = 50) [14]; Moroccan Arabs “M-AR”(n = 60), Moroccan Berbers “M-B”(n = 49) [18]; Andalusians“T-AN”(n = 132) and cosmopolitan (Tunisi) “T-T”Tunisians (n = 54) [19]; Tunisian Berbers “T-B”(n = 66) [20]; Portuguese “POR”(n = 250) [21]; Sicilians “SIC”(n = 255) [22]; Spaniards from Andalusia “SPA”(n = 56) [23] (PDF 14 KB)
Table S1
Complete Y-SNP typing results and haplogroups observed in the Algerian population sample (XLS 28 KB)
Table S2
Complete list of Y-chromosomal haplotypes observed in the Algerian population sample (XLS 32 KB)
Table S3
Pairwise distance (RST) between Algerian Arabs (A-AR) and eleven reference populations: Algerian Berbers “A-B” (n = 16), northern “E-N” (n = 47) and southern Egyptians “E-S” (n = 50) [14]; Moroccan Arabs “M-AR” (n = 60), Moroccan Berbers “M-B” (n = 49) [18]; Andalusians “T-AN” (n = 132) and cosmopolitan (Tunisi) “T-T” Tunisians (n = 54) [19]; Tunisian Berbers “T-B” (n = 66) [20]; Portuguese “POR” (n = 250) [21]; Sicilians “SIC” (n = 255) [22]; Spaniards from Andalusia “SPA” (n = 56) [23]. RST and p values are shown below and above the diagonal, respectively. Significant comparisons are shown in bold (PDF 30 KB)
Table S4
Most frequent Y-STR alleles within major haplogroups found in the Algerian population sample (unique alleles are underlined) (PDF 24 KB)
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Robino, C., Crobu, F., Di Gaetano, C. et al. Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample. Int J Legal Med 122, 251–255 (2008). https://doi.org/10.1007/s00414-007-0203-5
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DOI: https://doi.org/10.1007/s00414-007-0203-5