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Link to original content: https://doi.org/10.1007/BFb0056347
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Case-Based design for tablet formulation

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Advances in Case-Based Reasoning (EWCBR 1998)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 1488))

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Abstract

Case-Based Design (CBD) applies a knowledge-based process to the knowledge commonly associated with Case-Based Reasoning (CBR) systems — the library of exemplars. This paper investigates the problems in using commercial CBR tools, primarily aimed at classification applications, for a more knowledge intensive CBD task, and proposes techniques that overcome some of these difficulties. This work results from the development of a pharmaceutical CBD system Cbr-Tfs that proposes tablet formulations in order to manufacture viable tablets. Results show that Cbr-Tfs proposes useful ingredients for the tablet, and that the quantities it suggests are well within the limits of the tablet manufacturing process. CBD's increased need for specialised adaptation knowledge is also highlighted and this raises the issue of its acquisition.

The work reported here underpins a recently awarded EPSRC grant (GR/L98015) that aims to provide automated tools that assist knowledge acquisition for CBD.

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Author information

Authors and Affiliations

  1. School of Computer and Mathematical Sciences, The Robert Gordon University, St Andrew Street, AB25 1HG, Aberdeen, UK

    Susan Craw & Nirmalie Wiratunga

  2. Hurdsfield Industrial Estate, ZENECA Pharmaceuticals, SK10 2NA, Macclesfield, Cheshire, UK

    Ray Rowe

Authors
  1. Susan Craw
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  2. Nirmalie Wiratunga
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  3. Ray Rowe
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Editor information

Barry Smyth Pádraig Cunningham

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© 1998 Springer-Verlag Berlin Heidelberg

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Craw, S., Wiratunga, N., Rowe, R. (1998). Case-Based design for tablet formulation. In: Smyth, B., Cunningham, P. (eds) Advances in Case-Based Reasoning. EWCBR 1998. Lecture Notes in Computer Science, vol 1488. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0056347

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  • DOI: https://doi.org/10.1007/BFb0056347

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-64990-8

  • Online ISBN: 978-3-540-49797-4

  • eBook Packages: Springer Book Archive

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