Abstract
Disseminated cytomegalovirus infection in patients with AIDS usually involves the lungs, retina, esophagus, or colon. Gastrointestinal involvement may present clinically with fever, intractable diarrhea, and crampy abdominal pain. Ulcerations have been seen throughout the gastrointestinal tract, but perforations have been confined to the terminal ileum and colon. We report a case of a patient who presented with peritonitis with no prodromal symptoms and who, on exploration, had multiple large jejunal perforations secondary to cytomegalovirus enteropathy.
Similar content being viewed by others
References
Fernandes B, Brunton J, Koven I: Ileal perforation due to cytomegaloviral enteritis. Can J Surg 29:453–456, 1986
Frank D, Raicht R: Intestinal perforation associated with cytomegalovirus infection in patients with acquired immune deficiency syndrome. Am J Gastroenterol 79:201–205, 1984
Mintz L, Drew L, Miner RC, et al: Cytomegalovirus infections in homosexual men: an epidemological study. Ann Intern Med 99:326–329, 1983
Collaborative DHPG Treatment Study Group: Treatment of serious cytomegalovirus infections with 9-(1,3-dihydroxy-2-propoxy-methyl)guanine in patients with AIDS and other immunodeficiencies. N Engl J Med 314:801–805, 1986
Gertler SL, Pressman E, Price P, et al: Gastrointestinal cytomegalovirus infection in a homosexual man with severe acquired immunodeficiency syndrome. Gastroenterology 85:1403–1406, 1983
Knapp AB, Horst DA, Eliopoulous, et al: Widespread cytomegalovirus gastroenterocolitis in a patient with a acquired immunodeficiency syndrome. Gastroenterology 85:1399–1402, 1983
Robinson G, Wilson SE, Williams RA: Surgery in patients with acquired immunodeficiency syndrome. Arch Surg 122:170–175, 1987
Kram HB, Hino ST, Randy EC, et al: Spontaneous colonic perforations secondary to cytomegalovirus in a patient with acquired immune deficiency syndrome. Crit Care Med 12:469–471, 1984
Goodman ZD, Boitnott JK, Yardley JH: Perforation of the colon associated with cytomegalovirus infection. Dig Dis Sci 24:376–380, 1979
Nelson JA, Wiley CA, Reynolds-Kohler C, et al: Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms. Lancet 1:259–262, 1988
Laskin OL, Cederberg DM, Mills J, Eron L, Mildvan D, Spector S: Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus. Am J Med 83:201–207, 1987
Chachoua A, Dieterich D, Krasinski K, Greene J, Laubenstein L, Wernz J, Buhles W, Koretz S: 9-(1,3-dihydroxy-2-propoxy-methyl)guanine (gancyclovir) in the treatment of cytomegalovirus gastrointestinal disease with the acquired immunodeficiency syndrome. Ann Intern Med 107:133–137, 1987
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DeRiso, A.J., Kemeny, M.M., Torres, R.A. et al. Multiple jejunal perforations secondary to cytomegalovirus in a patient with acquired immune deficiency syndrome. Digest Dis Sci 34, 623–629 (1989). https://doi.org/10.1007/BF01536342
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01536342