Abstract
Comparing bacterial genomes implies the use of a dedicated measure. It relies on comparing circular genomes based on a set of conserved genes. Following this assumption, the common interval appears to be a good candidate. For evidences, we propose herein an approach to compute the common intervals between two circular genomes that takes into account duplications. Its application on a concrete case, comparing E. coli and V. cholerae, is accurate. It indeed emphasizes sets of conserved genes that present high impacts on bacterial functions.
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Angibaud, S., Eveillard, D., Fertin, G., Rusu, I. (2009). Comparing Bacterial Genomes by Searching Their Common Intervals. In: Rajasekaran, S. (eds) Bioinformatics and Computational Biology. BICoB 2009. Lecture Notes in Computer Science(), vol 5462. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00727-9_12
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DOI: https://doi.org/10.1007/978-3-642-00727-9_12
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