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Link to original content: https://doi.org/10.1007/978-3-319-16480-9_22
SimpLiSMS: A Simple, Lightweight and Fast Approach for Structured Motifs Searching | SpringerLink
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SimpLiSMS: A Simple, Lightweight and Fast Approach for Structured Motifs Searching

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Bioinformatics and Biomedical Engineering (IWBBIO 2015)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 9044))

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Abstract

A Structured Motif refers to a sequence of simple motifs with distance constraints. We present SimpLiSMS, a simple, lightweight and fast algorithm for searching structured motifs. SimpLiSMS does not use any sophisticated data structure, which makes it simple and lightweight. Our experiments show excellent performance of SimpLiSMS. Furthermore, we introduce a parallel version of SimpLiSMS which runs even faster.

Part of this research has been supported by an INSPIRE Strategic Partnership Award, administered by the British Council, Bangladesh for the project titled “Advances in Algorithms for Next Generation Biological Sequences”.

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References

  1. Aho, A.V., Corasick, M.J.: Efficient string matching: an aid to bibliographic search. Communications of the ACM 18(6), 333–340 (1975)

    Article  MATH  MathSciNet  Google Scholar 

  2. Bailey, T.L., Bodén, M., Buske, F.A., Frith, M.C., Grant, C.E., Clementi, L., Ren, J., Li, W.W., Noble, W.S.: MEME SUITE: tools for motif discovery and searching. Nucleic Acids Research 37(Web-Server-Issue), 202–208 (2009)

    Article  Google Scholar 

  3. Bailey, T.L., Williams, N., Misleh, C., Li, W.W.: MEME: discovering and analyzing DNA and protein sequence motifs. Nucleic Acids Research 34(Web-Server-Issue), 369–373 (2006)

    Article  Google Scholar 

  4. Bille, P., Gortz, I.L., Vildhoj, H.W., Wind, D.K.: String matching with variable length gaps. Theor. Comput. Sci. 443, 25–34 (2012)

    Article  MATH  MathSciNet  Google Scholar 

  5. Bille, P., Thorup, M.: Regular expression matching with multi–strings and intervals. In: Charikar, M. (ed.) ACM–SIAM Symp. on Discrete Algorithms, pp. 1297–1308. SIAM (2010)

    Google Scholar 

  6. Boyer, R.S., Moore, J.S.: A fast string searching algorithm. Communications of the ACM 20(10), 762–772 (1977)

    Article  MATH  Google Scholar 

  7. Crochemore, M., Sagot, M.-F.: 1. motifs in sequences. In: Compact Handbook of Computational Biology, p. 47 (2004)

    Google Scholar 

  8. Grundy, W.N., Bailey, T.L., Elkan, C., Baker, M.E.: Meta-meme: motif-based hidden markov models of protein families. Computer Applications in the Biosciences 13(4), 397–406 (1997)

    Google Scholar 

  9. Halachev, M., Shiri, N.: Fast structured motif search in DNA sequences. In: Elloumi, M., Küng, J., Linial, M., Murphy, R.F., Schneider, K., Toma, C. (eds.) BIRD 2008. CCIS, vol. 13, pp. 58–73. Springer, Heidelberg (2008)

    Google Scholar 

  10. Hulo, N., Bairoch, A., Bulliard, V., Cerutti, L., De Castro, E., Langendijk-Genevaux, P.S., Pagni, M., Sigrist, C.J.A.: The prosite database. Nucleic Acids Research 34(suppl. 1), D227–D230 (2006)

    Google Scholar 

  11. Junier, T., Pagni, M., Bucher, P.: mmsearch: a motif arrangement language and search program. Bioinformatics 17(12), 1234–1235 (2001)

    Article  Google Scholar 

  12. Knuth, D.E., Morris, J.H., Pratt, V.R.: Fast pattern matching in strings. SIAM Journal of Computing 6(2), 323–350 (1977)

    Article  MATH  MathSciNet  Google Scholar 

  13. Morgante, M., Policriti, A., Vitacolonna, N., Zuccolo, A.: Structured motifs search. Journal of Computational Biology 12(8), 1065–1082 (2005)

    Article  Google Scholar 

  14. Navarro, G., Raffinot, M.: Fast and simple character classes and bounded gaps patternmatching, with application to protein searching. In: RECOMB, pp. 231–240 (2001)

    Google Scholar 

  15. Navarro, G., Raffinot, M.: Fast and simple character classes and bounded gaps pattern matching, with applications to protein searching. Journal of Computational Biology 10(6), 903–923 (2003)

    Article  Google Scholar 

  16. Pissis, S.P.: Motex-ii: structured motif extraction from large-scale datasets. BMC Bioinformatics 15, 235 (2014)

    Article  Google Scholar 

  17. Rahman, M.S., Iliopoulos, C.S., Lee, I., Mohamed, M., Smyth, W.F.: Finding patterns with variable length gaps or don’t cares. In: Chen, D.Z., Lee, D.T. (eds.) COCOON 2006. LNCS, vol. 4112, pp. 146–155. Springer, Heidelberg (2006)

    Chapter  Google Scholar 

  18. Sigrist, C.J.A., de Castro, E., Cerutti, L., Cuche, B.A., Hulo, N., Bridge, A., Bougueleret, L., Xenarios, I.: New and continuing developments at prosite. Nucleic Acids Research 41(D1), D344–D347 (2013)

    Google Scholar 

  19. Zhang, Y., Zaki, M.J.: SMOTIF: efficient structured pattern and profile motif search. Algorithms for Molecular Biology, 1 (2006)

    Google Scholar 

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Alatabbi, A., Azmin, S., Habib, M.K., Iliopoulos, C.S., Rahman, M.S. (2015). SimpLiSMS: A Simple, Lightweight and Fast Approach for Structured Motifs Searching. In: Ortuño, F., Rojas, I. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2015. Lecture Notes in Computer Science(), vol 9044. Springer, Cham. https://doi.org/10.1007/978-3-319-16480-9_22

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  • DOI: https://doi.org/10.1007/978-3-319-16480-9_22

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-16479-3

  • Online ISBN: 978-3-319-16480-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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