Acetaminophen; Hydrocodone

Drug Usage Statistics, United States, 2013 - 2022

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Acetaminophen; Hydrocodone Summary for 2022

Top drug rank	#23 ( 3)
Estimated number of prescriptions in the United States (2022)	23,521,228
Estimated number of patients in the United States (2022)	7,972,417
Average total drug cost (USD)
Per prescription	$26.29
Per day of therapy	$1.96/day
Average out-of-pocket cost (USD)
Per prescription	$7.52
Per day of therapy	$0.75/day

Total Prescriptions and Patients Per Year (2013 - 2022)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Drug Cost Over Time (2013 - 2022)

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2022)

Dosage Form	Strength	% of Dispensed Products
Tablet/capsule	7.5/325 mg/mg	75.6%
Tablet/capsule	5-325 mg	23.1%
Other, unspecified, or misc.		1.3%

Distribution of Days Supplied (2022)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

FDA Approval Information

Established Pharmacologic Class (EPC):	Opioid Agonist
Initial FDA approval date:	Prior to January 1, 1982
First FDA applicant:	Discn
First dosage form:	Tablet (oral)

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Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2022. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.08. Read more about the ClinCalc DrugStats database.

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