rivastigmine (Q411887)

has use

medication

0 references

chemical structure

Rivastigmine chemical structure.svg
237 × 87; 5 KB

0 references

mass

250.168128 dalton

1 reference

rivastigmine (English)

3 October 2016

2 references

based on heuristic

inferred from InChI

chemical formula

C₁₄H₂₂N₂O₂

1 reference

rivastigmine (English)

19 November 2016

canonical SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C

1 reference

rivastigmine (English)

19 November 2016

isomeric SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C

1 reference

rivastigmine (English)

19 November 2016

defined daily dose

9 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=N06DA03

active ingredient in

Exelon

1 reference

EMEA/H/C/000169

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000169/human_med_000777.jsp

22 March 2017

Nimvastid

1 reference

EMEA/H/C/001029

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001029/human_med_000930.jsp

22 March 2017

Prometax

1 reference

EMEA/H/C/000255

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000255/human_med_000996.jsp

22 March 2017

Rivastigmine 1 A Pharma

1 reference

EMEA/H/C/001181

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001181/human_med_001210.jsp

Rivastigmine 3m Health Care Ltd

22 March 2017

1 reference

EMEA/H/C/003824

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003824/human_med_001738.jsp

22 March 2017

Rivastigmine Hexal

1 reference

EMEA/H/C/001182

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001182/human_med_001211.jsp

22 March 2017

Rivastigmine Sandoz

1 reference

EMEA/H/C/001183

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001183/human_med_001212.jsp

22 March 2017

Rivastigmine Teva

1 reference

EMEA/H/C/001044

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001044/human_med_001041.jsp

World Health Organisation international non-proprietary name

22 March 2017

rivastigmine (English)

2 references

rivastigmine (English)

medical condition treated

3 October 2016

published in

Recommended INN: List 39

publication date

1998

early-onset Alzheimer's disease

1 reference

13 December 2016

2 references

13 December 2016

2 October 2018

Parkinson's disease

1 reference

2 October 2018

Alzheimer's disease

1 reference

2 October 2018

Lewy body dementia

1 reference

Food and Drug Administration

2 October 2018

6 July 2007

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/PKI06M3IW0

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020823s035,021025s023lbl.pdf

Alzheimer's disease

start time

6 July 2007

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/PKI06M3IW0

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020823s035,021025s023lbl.pdf

significant drug interaction

donepezil

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-metoprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nadolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atenolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nebivolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

acebutolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

betaxolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bisoprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pindolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

carvedilol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

propranolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sotalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

labetalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celiprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

esmolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

levobunolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

17 August 2016

butyrylcholinesterase

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

imported from Wikimedia project

17 August 2016

pregnancy category

US pregnancy category B

1 reference

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category D

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Rivastigmine

last update

15 January 2020

subject has role

acetylcholinesterase inhibitor

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

D000068836

15 March 2018

neuroprotective agent

1 reference

InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1

Medical Subject Headings

15 March 2018

Rivastigmine

0 references

Identifiers

InChI

1 reference

rivastigmine (English)

19 November 2016

2 references

rivastigmine (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

123441-03-2

2 references

rivastigmine (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=123441-03-2

9 April 2021

1 reference

Rivastigmine (English)

19 November 2016

2 references

rivastigmine (English)

19 November 2016

Reaxys registry number

7875788

1 reference

rivastigmine (English)

3 October 2016

ChEBI ID

8874

mapping relation type

2 references

RIVASTIGMINE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1

1 reference

RIVASTIGMINE (English)

19 November 2016

2 references

splash10-0a4i-1090000000-d7335c9ff57f34335d3c

1 reference

MassBank accession ID

0 references

0 references

0 references

0 references

0 references

0 references

0 references

splash10-052r-9050000000-2739573cc72accdb3593

0 references

splash10-052r-9010000000-827dd9cfa5e61c705617

0 references

splash10-052r-9000000000-42e62adc5ba35b92f991

0 references

splash10-0a4i-9000000000-717721d4d1b05cfae7d9

0 references

DSSTox substance ID

DTXSID7023564

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.120.679

27 December 2018

ECHA Substance Infocard ID

(+)-N-Ethyl-N-methyl-3-[1-(dimethylamino)ethyl]phenylcarbamate (English)

quotation

CAS no.: 123441-03-2 (English)

100.120.679

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.120.679

27 December 2018

(+)-N-Ethyl-N-methyl-3-[1-(dimethylamino)ethyl]phenylcarbamate (English)

quotation

CAS no.: 123441-03-2 (English)

1 reference

World Health Organisation international non-proprietary name numeric ID

Rivastigmine (English)

publication date

17 November 2015

7562

1 reference

https://mednet-communities.net/inn/db/ViewINN.aspx?i=7562

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

rivastigmine (English)

19 November 2016

Rivastigmine

0 references

MeSH tree code

D02.241.081.251.583.899

0 references

RxNorm ID

183379

1 reference

rivastigmine (English)

19 November 2016

DrugBank ID

DB00989

1 reference

Human Metabolome Database ID

HMDB0015124

2 references

based on heuristic

2 references

rivastigmine (English)

19 November 2016

MedlinePlus drug identifier

a602009

route of administration

oral administration

0 references

a607078

route of administration

transdermal administration

0 references

NDF-RT ID

N0000148665

1 reference

rivastigmine (English)

19 November 2016

0 references

1 reference

1 reference

rivastigmine (English)

3 October 2016

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

rivastigmine (English)

3 October 2016

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0649350

1 reference

rivastigmine (English)