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Link to original content: http://www.ncbi.nlm.nih.gov/pubmed/24521025
Genome-wide association studies and the clinic: a focus on breast cancer - PubMed Skip to main page content
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Review
. 2014;8(2):287-96.
doi: 10.2217/bmm.13.121.

Genome-wide association studies and the clinic: a focus on breast cancer

Amélie Véron  1 , Sophie Blein, David G Cox
Affiliations
Review

Genome-wide association studies and the clinic: a focus on breast cancer

Amélie Véron et al. Biomark Med. 2014.

Abstract

Breast cancer is the most frequently diagnosed cancer among women worldwide, and has long been considered to be a genetic disease. A wide range of genetic variants, both rare mutations and more common variants, have been shown to influence breast cancer risk. In particular, recent studies have identified a number of common genetic variants, or single nucleotide polymorphisms, that are associated with breast cancer risk. In this review, we will briefly present the genetic epidemiology of breast cancer, genome-wide association study technology and how this technology may influence breast cancer screening in the clinic.

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