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Link to original content: http://www.ncbi.nlm.nih.gov/pubmed/23474917
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Review
. 2013 Oct;36(5):1190-203.
doi: 10.1007/s00270-013-0592-4. Epub 2013 Mar 9.

MR-guided high-intensity focused ultrasound: current status of an emerging technology

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Review

MR-guided high-intensity focused ultrasound: current status of an emerging technology

Alessandro Napoli et al. Cardiovasc Intervent Radiol. 2013 Oct.

Abstract

The concept of ideal tumor surgery is to remove the neoplastic tissue without damaging adjacent normal structures. High-intensity focused ultrasound (HIFU) was developed in the 1940s as a viable thermal tissue ablation approach. In clinical practice, HIFU has been applied to treat a variety of solid benign and malignant lesions, including pancreas, liver, prostate, and breast carcinomas, soft tissue sarcomas, and uterine fibroids. More recently, magnetic resonance guidance has been applied for treatment monitoring during focused ultrasound procedures (magnetic resonance-guided focused ultrasound, MRgFUS). Intraoperative magnetic resonance imaging provides the best possible tumor extension and dynamic control of energy deposition using real-time magnetic resonance imaging thermometry. We introduce the fundamental principles and clinical indications of the MRgFUS technique; we also report different treatment options and personal outcomes.

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