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Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy

Joseph D. Butner
Prashant Dogra
Zhihui Wang

Article 14 August 2024

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A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence

Alexis Hernández-Magaña
Antonio Bensussen
Elena R. Álvarez-Buylla
ArticleOpen Access02 Sept 2024
Systems immunology approaches to study T cells in health and disease

Aaron Yang
Amanda C. Poholek
Review ArticleOpen Access09 Oct 2024
A web portal for exploring kinase-substrate interactions

John A. P. Sekar
Yan Chak Li
Gaurav Pandey
ArticleOpen Access03 Oct 2024
Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations

Andrea L. Gardner
Tyler A. Jost
Amy Brock
ArticleOpen Access17 Oct 2024

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npj Systems Biology and Applications Journal Metrics

npj Systems Biology and Applications has a 2-year impact factor of 3.5 (2023), article downloads of 306,030 (2023) and 2 days from submission to first editorial decision (median) in 2023.
Call for papers: Virtual human development

This Collection invites research leveraging experimental and theoretical models, and advanced research tools to study human development.

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Call for papers: Methodological developments in systems

This collection calls for papers that focus on the latest computational and modelling developments in systems biology research.

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Call for papers on mathematical oncology

Mathematical and computational oncology are rapidly emerging as critical areas of research that aim to understand the intricate and complex nature of cancer. We invite submissions from both early career and senior researchers, and particularly encourage research with high translational value.

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Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis

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Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development

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An integrative network-based approach to identify driving gene communities in chronic obstructive pulmonary disease

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Faculty Positions at SUSTech School of Medicine

SUSTech School of Medicine offers equal opportunities and welcome applicants from the world with all ethnic backgrounds.

Shenzhen, Guangdong, China

Southern University of Science and Technology, School of Medicine
Faculty Positions at the Center for Advanced Microbiome Research

Faculty Positions in Microbiome Research at the Center for Advanced Microbiome Research and Innovation, Institute for Genome Sciences, UM SOM

Baltimore, Maryland

Institute for Genome Sciences, University of Maryland School of Medicine
Postdoctoral fellows in molecular plant physiology and metabolic engineering

Postdoc1. Exploration of ACC, a novel signaling molecule in plants. Postdoc2. Vitamin interactions and biofortification of crops.

Ghent, Gand (BE)

Laboratory of Functional Plant Biology - Ghent University
2024 Recruitment notice Shenzhen Institute of Synthetic Biology: Shenzhen, China

The wide-ranging expertise drawing from technical, engineering or science professions...

Shenzhen,China

Shenzhen Institute of Synthetic Biology
Faculty Positions in School of Engineering, Westlake University

The School of Engineering (SOE) at Westlake University is seeking to fill multiple tenured or tenure-track faculty positions in all ranks.

Hangzhou, Zhejiang, China

Westlake University

This journal is a member of and subscribes to the principles of the Committee on Publication Ethics.

Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy

Featured

A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence

Systems immunology approaches to study T cells in health and disease

A web portal for exploring kinase-substrate interactions

Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations

Announcements

npj Systems Biology and Applications Journal Metrics

Call for papers: Virtual human development

Call for papers: Methodological developments in systems

Call for papers on mathematical oncology

Browse articles

Plasmodium vivax antigen candidate prediction improves with the addition of Plasmodium falciparum data

Experimentally-driven mathematical model to understand the effects of matrix deprivation in breast cancer metastasis

Automatic construction of Petri net models for computational simulations of molecular interaction network

Reliable and easy-to-use calculating tool for the Nail Psoriasis Severity Index using deep learning

Exploring heterogeneous cell population dynamics in different microenvironments by novel analytical strategy based on images

Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis

Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development

Multi-bioinformatics revealed potential biomarkers and repurposed drugs for gastric adenocarcinoma-related gastric intestinal metaplasia

An integrative network-based approach to identify driving gene communities in chronic obstructive pulmonary disease

Trending - Altmetric

Science jobs

Faculty Positions at SUSTech School of Medicine

Faculty Positions at the Center for Advanced Microbiome Research

Postdoctoral fellows in molecular plant physiology and metabolic engineering

2024 Recruitment notice Shenzhen Institute of Synthetic Biology: Shenzhen, China

Faculty Positions in School of Engineering, Westlake University

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Nobel Turing Challenge: creating the engine for scientific discovery

Emergence of cyclic hypoxia and the impact of PARP inhibitors on tumor progression

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