| Entry |
|
|---|
| Name |
Denopamine (JAN/INN);
Kalgut (TN) |
|---|
| Formula |
C18H23NO4
|
|---|
| Exact mass |
317.1627
|
|---|
| Mol weight |
317.38
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01451 beta1-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
|
|---|
| Remark |
| Therapeutic category: | 2119 |
|
|---|
| Efficacy |
Cardiotonic, beta1-Adrenergic receptor agonist |
|---|
| Comment |
Dopamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07214 | beta-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2119 Others
D02614 Denopamine (JAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
D02614 Denopamine
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01451 beta1-Adrenergic receptor agonist
D02614 Denopamine
DG01951 Catecholamine adrenergic receptor agonist
D02614 Denopamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D02614 Denopamine (JAN/INN) <JP>
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C1a C 8.6800 -17.7800
2 C1a C 8.6800 -19.1800
3 O2a O 9.8924 -19.8800
4 C8y C 11.1049 -19.1800
5 C8y C 11.1049 -17.7800
6 O2a O 9.8924 -17.0800
7 C8x C 12.3173 -19.8800
8 C8x C 13.5297 -19.1800
9 C8y C 13.5297 -17.7800
10 C8x C 12.3173 -17.0800
11 C1b C 14.7273 -17.0885
12 C1b C 15.9156 -17.7745
13 N1b N 17.1064 -17.0869
14 C1b C 18.2960 -17.7737
15 C1c C 19.4861 -17.0865
16 C8y C 20.6762 -17.7735
17 O1a O 19.4862 -15.6802
18 C8x C 20.6763 -19.1798
19 C8x C 21.8888 -19.8796
20 C8y C 23.1012 -19.1795
21 C8x C 23.1010 -17.7733
22 C8x C 21.8885 -17.0734
23 O1a O 24.3130 -19.8791
BOND 24
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 1 6 1
6 4 7 2
7 7 8 1
8 8 9 2
9 9 10 1
10 5 10 2
11 9 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 15 17 1 #Down
18 16 18 2
19 18 19 1
20 19 20 2
21 20 21 1
22 21 22 2
23 16 22 1
24 20 23 1
|
|---|
