prefix (n.)

late 14c., "set (one's eyes or mind) on something" (a figurative use), probably from Old French verb *fixer, from fixe "fixed," from Latin fixus "fixed, fast, immovable; established, settled," past-participle adjective from figere "to fix, fasten, drive, thrust in; pierce through, transfix," also figurative, from PIE root *dheigw- "to pierce, stick in;" hence "to fix, fasten."

Sense of "fasten, attach" is c. 1400; that of "to make (colors, etc.) fast or permanent" is from 1660s. The meaning "settle, assign" evolved into "adjust, arrange" (1660s), then "to repair" (1737), but this sometimes was objected to (see below). Sense of "tamper with" (a fight, a jury, etc.) is from 1790. As euphemism for "castrate a pet" it dates from 1930. Related: Fixed; fixing.

To fix is to make fast, or permanent; to set immoveably, &c.: hence, to fix a watch, is to stop it, or prevent it from 'going;' which, it must be admitted, is a very unsatisfactory mode of repairing that article. [Seth T. Hurd, "A Grammatical Corrector; or, Vocabulary of the Common Errors of Speech," 1847]

Proto-Indo-European root meaning "to stick, fix." 

It forms all or part of: affix; crucifix; crucify; dig; dike; ditch; fibula; fiche; fichu; fix; fixate; fixation; fixity; fixture; infibulate; infibulation; microfiche; prefix; suffix; transfix.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit dehi- "wall;" Old Persian dida "wall, stronghold, fortress," Persian diz; Latin figere "to fix, fasten, drive, thrust in; pierce through, transfix;" Lithuanian dygstu, dygti "germinate;" Old Irish dingid "presses, thrusts down;" Old English dic "trench, ditch," Dutch dijk "dam." 

word-forming element meaning "before," from Old French pre- and Medieval Latin pre-, both from Latin prae (adverb and preposition) "before in time or place," from PIE *peri- (source also of Oscan prai, Umbrian pre, Sanskrit pare "thereupon," Greek parai "at," Gaulish are- "at, before," Lithuanian prie "at," Old Church Slavonic pri "at," Gothic faura, Old English fore "before"), extended form of root *per- (1) "forward," hence "beyond, in front of, before."

The Latin word was active in forming verbs. Also see prae-. Sometimes in Middle English muddled with words in pro- or per-.