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Testosterone enantate benzilic acid hydrazone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Identification

Generic Name
Testosterone enantate benzilic acid hydrazone
DrugBank Accession Number
DB13947
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
3D
Similar Structures
Weight
Average: 624.866
Monoisotopic: 624.392708162
Chemical Formula
C40H52N2O4
Synonyms
  • Testosterone 17-enanthate 3-benzilic acid hydrazone
  • Testosterone enanthate benzilic acid hydrazone
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available
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Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
AbciximabTestosterone enantate benzilic acid hydrazone may increase the anticoagulant activities of Abciximab.
AcenocoumarolTestosterone enantate benzilic acid hydrazone may increase the anticoagulant activities of Acenocoumarol.
AlteplaseTestosterone enantate benzilic acid hydrazone may increase the anticoagulant activities of Alteplase.
AncrodTestosterone enantate benzilic acid hydrazone may increase the anticoagulant activities of Ancrod.
AnistreplaseTestosterone enantate benzilic acid hydrazone may increase the anticoagulant activities of Anistreplase.
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Climacteron InjectionTestosterone enantate benzilic acid hydrazone (150 mg / mL) + Estradiol benzoate (1 mg / mL) + Estradiol dienanthate (7.5 mg / mL)LiquidIntramuscularSandoz S.P.A.1994-12-312005-10-20Canada flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as steroid esters. These are compounds containing a steroid moiety which bears a carboxylic acid ester group.
Kingdom
Organic compounds
Super Class
Lipids and lipid-like molecules
Class
Steroids and steroid derivatives
Sub Class
Steroid esters
Direct Parent
Steroid esters
Alternative Parents
Androstane steroids / Delta-4-steroids / Diphenylmethanes / Phenylacetamides / Tertiary alcohols / Carboxylic acid esters / Monocarboxylic acids and derivatives / Organonitrogen compounds / Organic oxides / Hydrocarbon derivatives
show 2 more
Substituents
Alcohol / Androstane-skeleton / Aromatic alcohol / Aromatic homopolycyclic compound / Benzenoid / Carbonyl group / Carboxylic acid derivative / Carboxylic acid ester / Delta-4-steroid / Diphenylmethane
show 11 more
Molecular Framework
Aromatic homopolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
X8Z8A2G2Y4
CAS number
18625-33-7
InChI Key
PTVXYACXDYZNID-JKXGKYMWSA-N
InChI
InChI=1S/C40H52N2O4/c1-4-5-6-13-18-36(43)46-35-22-21-33-32-20-19-30-27-31(23-25-38(30,2)34(32)24-26-39(33,35)3)41-42-37(44)40(45,28-14-9-7-10-15-28)29-16-11-8-12-17-29/h7-12,14-17,27,32-35,45H,4-6,13,18-26H2,1-3H3,(H,42,44)/t32-,33-,34-,35-,38-,39-/m0/s1
IUPAC Name
(1S,3aS,3bR,9aR,9bS,11aS)-7-[(2-hydroxy-2,2-diphenylacetamido)imino]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl heptanoate
SMILES
[H]N(N=C1CC[C@@]2(C)C(CC[C@@]3([H])[C@]4([H])CC[C@H](OC(=O)CCCCCC)[C@@]4(C)CC[C@]23[H])=C1)C(=O)C(O)(C1=CC=CC=C1)C1=CC=CC=C1

References

General References
Not Available
ChemSpider
34995240
ZINC
ZINC000299888598
Wikipedia
Testosterone_enantate_benzilic_acid_hydrazone

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000122 mg/mLALOGPS
logP6.54ALOGPS
logP8.49Chemaxon
logS-6.7ALOGPS
pKa (Strongest Acidic)11.09Chemaxon
pKa (Strongest Basic)2.14Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area87.99 Å2Chemaxon
Rotatable Bond Count11Chemaxon
Refractivity182.37 m3·mol-1Chemaxon
Polarizability74.51 Å3Chemaxon
Number of Rings6Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a6r-0000619000-25496d25fb642060b4c3
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-00di-1100109000-461f410f33bf949177ac
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-002b-0016913000-11f3b96357b3b5a294c6
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9700311000-dfa2473a55ff0558367e
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-03fr-3109551000-5bef8473b1adb37d747c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-052f-9000000000-e13df9fa72a7f305cc3e
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-240.09027
predicted
DeepCCS 1.0 (2019)
[M+H]+241.91515
predicted
DeepCCS 1.0 (2019)
[M+Na]+247.65852
predicted
DeepCCS 1.0 (2019)

Drug created at January 11, 2018 23:14 / Updated at June 12, 2020 16:53