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Link to original content: http://www.chemicalland21.com/lifescience/foco/CALCIUM PANTOTHENATE.htm
CALCIUM PANTOTHENATE (VITAMIN B-5)

 

CALCIUM D-PANTOTHENATE

PRODUCT IDENTIFICATION

CAS NO. 137-08-6

CALCIUM PANTOTHENATE

EINECS NO.

205-278-9

FORMULA C18H32CaN2O10
MOL WT. 476.54

HS CODE

293624

SMILES

 

TOXICITY

Oral rat LD50: > 10 gram/kg
SYNONYMS Calcium D-(+)-pantothenate; Calcium salt of Pantothenic acid;
Pantholin; Vitamin B-5; N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine Calcium;

CLASSIFICATION

VITAMINS /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White crystalline solid, Odorless
MELTING POINT 196 C Decomposes
BOILING POINT

 

SPECIFIC GRAVITY

 

SOLUBILITY Easily in water, slightly in alcohol ,hardly in chloroform, ethyl ether.
pH neutral or weak base
VAPOR DENSITY

 

FLASH POINT

 

APPLICATIONS

Pantothenic acid, the amide of beta-alanine and pantoic acid, is a B complex vitamin acting as a precursor in the biosynthesis of coenzyme A, involved in the metabolism as an antioxidant to breakdown many biochemical substances (fatty acids, steroids, phospholipids, heme, amino acids, and carbohydrates). The adrenal gland is an important site of pantothenic acid activity. It can be found ubiquitously in foods, and no deficiency syndrome has been demonstrated in humans except by experimental administration of the pantothenic acid antagonist (omega-methylpantothenic acid). Pantothenic acid is an unstable oil. The usual forms for feed supplementation are its salts, calcium D-pantothenate, sodium D-pantothenate and D-panthenol (liquid). Both salts are white hygroscopic powders easily soluble in water. D-Panthenol is a colourless viscous oil form which may turn to crystalline solid during storage (Racemic mixture is a solid form melting point 65C). Two enantiomers exit, D or L-form. D-panthenol is biologically active. But both forms show moisturizing properties. Panthenol is the alcohol analog of pantothenic acid. Panthenol is converted to pantothenic acid in the body. Panthenol is called provitamin B5.

Pantetheine [2,4-Dihydroxy-N-(2-((2-merceptoethyl)carbamoyl)ethyl)-3,3-dimethylbutyramide] is the amide analogue of pantothenic acid. Pantethine (bis-pantetheine) is formed naturally when reacted with beta-mercaptoethanolamine. This amide is an intermediate in the pathway of coenzyme A biosynthesis. Pantenicate [3-(3-Pyridinemethoxycarbonyl) propionic acid pantethine tetraester] is used as an antilipemic agent to reduce lipid levels in the blood (to treat hyperlipidemia).

PANTOTHENIC ACID MOLECULES

Product

CAS RN

alpha-Hydroxyhomopantothenic acid 1977-34-0
beta-Hydroxyhomopantothenic acid 1977-35-1
Calcium 4-phosphopantothenate 55816-28-9
Calcium D-pantothenate 15773-29-2
Calcium gamma-aminobutyratopantothenate 85625-91-8
Calcium hopantenate 17097-76-6
Calcium pantothenate hydrate 63409-48-3
Calcium Pantothenate racemic 6381-63-1
Calcium pantothenate 137-08-6
Calcium pantothenate, calcium chloride complex 6363-38-8
Chloramphenicol pantothenate complex 31342-36-6
Copper gamma-aminobutyratopantothenate 85625-88-3
Dexpanthenol 81-13-0
Dihydrostreptomycin pantothenate 3563-84-6
DL-Pantothenic acid 599-54-2
D-Panthothenyl trifarnesylacetate 15470-06-1
D-Pantothenamide 7757-97-3
D-Pantothenic acid 4'-O-beta-glucoside 29588-37-2
Homopantothenic acid 1977-33-9
Hopantenic acid 18679-90-8
Kanamycin dipantothenate 17899-96-6
Kanamycin monopantothenate 17899-71-7
L-Arginine pantothenate 23541-09-5
Manganese gamma-aminobutyratopantothenate 85625-90-7
Methyl pantothenate 50692-78-9
N-D-(+)-Pantothenoyl-gamma-aminobutyric acid 85647-53-6
Neomycin pantothenate 78149-94-7
Nickel gamma-aminobutyratopantothenate 85625-89-4
omega-Methyl pantothenic acid 2545-82-6

Pantetheine

496-65-1
Pantethine 16816-67-4
Pantethine 4',4''-diphosphate 2664-64-4
Pantenicate 96922-80-4
Panthenol 16485-10-2
Pantothenate ion 20938-62-9
Pantothenate permease 99194-01-1
Pantothenic acid 79-83-4
Pantothenylcysteine 4'-phosphate 7196-09-0
Pantoyltaurine 2545-84-8
Phosphopantothenic acid 5875-50-3
S-Benzylisothiouronium pantothenate 63680-25-1
Sodium omega-methyl pantothenate 59203-09-7
Sodium pantothenate 867-81-2
Streptomycin-pantothenate 6227-52-7
Viomycin pantothenate sulfate 1401-79-2
Zinc pantothenate 65979-81-9

SALES SPECIFICATION

 

USP GRADE

FEED GRADE

APPEARANCE

white powder, odorless

ASSAY

98.0 - 101.0%

45.0 - 55.0%

CALCIUM

8.2 - 8.6%

8.2 - 8.6%

NITROGEN

5.7 - 6.0%

5.7 - 6.0%

SPECIFIC ROTATION

+25° ~ +27.5°
-0.05° ~ +0.05°

HEAVY METALS

20ppm max

20ppm max

TRANSPORTATION
PACKING

25kgs in Fiber Drum

HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36