Statistics (01.2023)

Increase in the data content of BRENDA in the last years

ACTIVATING COMPOUNDS^*

18466

show all

38623

20157 (109%)

APPLICATIONS^*

29398

CAS REGISTRY NUMBERS^*

4517

CLONED^*

70794

COFACTORS^*

56910

CRYSTALLIZATIONS^*

19082

EC CLASSES

4762

8424

3662 (77%)

ENGINEERING/MUTATIONS^*

23234

119945

96711 (416%)

ENZYME SYNONYMS

53389

338439

285050 (534%)

EXPRESSION^*

12622

GENERAL INFORMATION^*

78779

GENERAL STABILITIES^*

8804

IC50 VALUES^*

69886

INHIBITORS^*

112470

298358

185888 (165%)

KCAT/KM VALUES^*

38626

KI VALUES^*

15736

46076

30340 (193%)

KM VALUES^*

79431

176610

97179 (122%)

LIGAND 2D STRUCTURES

38488

159192

120704 (314%)

LIGANDS^*

764282

2625795

1861513 (244%)

LOCALIZATION^*

19011

65031

46020 (242%)

METALS AND IONS^*

66371

NATURAL SUBSTRATES OF ENZYMATIC REACTIONS^*

51123

173436

122313 (239%)

ORGANIC SOLVENT STABILITIES^*

3610

ORGANISM

16018959

OXIDATION STABILITIES^*

961

pH OPTIMA^*

57293

pH RANGES^*

12998

pH STABILITIES^*

8814

pI VALUES^*

2060

7009

4949 (240%)

POSTTRANSLATIONAL MODIFICATIONS^*

12119

PURIFICATIONS^*

65397

REACTION TYPES^*

13980

REACTIONS

22912

REFERENCES

68366

167153

98787 (144%)

RENATURED^*

1393

SEQUENCES

283138

32832265

32549127 (11496%)

SOURCE TISSUE^*

44110

162209

118099 (268%)

SPECIFIC ACTIVITIES^*

59868

STORAGE STABILITIES^*

11370

SUBSTRATES AND PRODUCTS

511253

SUBUNITS^*

72360

TEMPERATURE OPTIMA^*

40549

TEMPERATURE RANGES^*

6601

TEMPERATURE STABILITIES^*

27079

TURNOVER NUMBERS^*

86919

^* = The numbers denote the enzyme-organism-(protein-)commentary-reference-specific occurrences. For kinetic values (Km, Ki, kcat) and ligand-specific fields (Inhibitors, Activating Compounds, Ligands) the corresponding enzyme ligand is also taken into account.

For example, when the identical pI (isoelectric point) was measured for different enzymes or the identical enzyme from different organisms the information is included for each EC number and organism-specific enzyme isoform, respectively.