Unilateral skin eruptions

A woman in her 40s, with a history of bronchial asthma and hypertension, presented with a seven day history of sudden onset bullous skin lesions, associated with itching and a burning sensation (fig 1). She had no personal or family history of bleeding disorders. The lesions initially appeared on her right foot, progressed to the right thigh, and then evolved to hyperpigmented macules within seven days (fig 2). She reported no history of fever, mucosal ulcers or lesions, dermatomal distribution of the rash, malaise, or joint pains. Four days before the onset of the lesions the patient had been prescribed levofloxacin for …