Eticlopride

Eticlopride
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide;
CAS Number	84226-12-0 ; HCl: 97612-24-3 ;
PubChem CID	57267;
IUPHAR/BPS	966;
ChemSpider	51626 ;
UNII	J8M468HBH4; HCl: HJ2CAH4TZ1 ;
ChEMBL	ChEMBL8946 ;
CompTox Dashboard (EPA)	DTXSID9048435 ;
Chemical and physical data
Formula	C17H25ClN2O3
Molar mass	340.85 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl;
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Eticlopride is a selective dopamine antagonist that acts on D₂ dopamine receptor. It is primarily used in pharmacological research.^[1]^[2]^[3]^[4]

References

^ "Eticlopride hydrochloride". Abcam.
^ Claytor R, Lile JA, Nader MA (March 2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys". Pharmacology, Biochemistry, and Behavior. 83 (3): 456–64. doi:10.1016/j.pbb.2006.03.007. PMID 16631246. S2CID 39482275.
^ Hemby SE, Smith JE, Dworkin SI (June 1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats". The Journal of Pharmacology and Experimental Therapeutics. 277 (3): 1247–58. PMID 8667185.
^ Haile CN, Kosten TA (November 2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats". The Journal of Pharmacology and Experimental Therapeutics. 299 (2): 509–18. PMID 11602661.

Eticlopride at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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