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Link to original content: http://wikipedia.org/wiki/Cloxazolam
Cloxazolam - Wikipedia Jump to content

Cloxazolam

From Wikipedia, the free encyclopedia

Cloxazolam
Clinical data
Trade namesAkton, Cloxam, Clozal, Elum, Olcadil, and Sepazon[1]
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
Pharmacokinetic data
MetabolismHepatic
Elimination half-life65 hours
ExcretionRenal
Identifiers
  • 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H14Cl2N2O2
Molar mass349.21 g·mol−1
3D model (JSmol)
  • Clc1ccccc1C42OCCN2CC(=O)Nc3c4cc(Cl)cc3
  • InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22) checkY
  • Key:ZIXNZOBDFKSQTC-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cloxazolam is a benzodiazepine derivative that has anxiolytic, sedative, and anticonvulsant properties.[3][4] It is not widely used; [3] as of August 2018 it was marketed in Belgium, Luxembourg, Portugal, Brazil, and Japan.[1] In 2019, it has been retired from the Belgian market. [5]

See also

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References

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  1. ^ a b "Cloxazolam International Brands". Drugs.com. Retrieved 13 August 2018.
  2. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  3. ^ a b Stolerman IP, ed. (2010). "C: Cloxazolam". Encyclopedia of Psychopharmacology. Berlin: Springer-Verlag. ISBN 978-3-540-68706-1.
  4. ^ Richards BL, Whittle SL, Buchbinder R (January 2012). "Muscle relaxants for pain management in rheumatoid arthritis". The Cochrane Database of Systematic Reviews. 1: CD008922. doi:10.1002/14651858.CD008922.pub2. PMID 22258993. S2CID 73769165.
  5. ^ "Bon à savoir". cbip.be. Retrieved 13 August 2018.
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