Cimoxatone

Cimoxatone
Clinical data
ATC code	none;
Identifiers
	IUPAC name 3-[[4-[5-(methoxymethyl)-2-oxo-oxazolidin-3-yl]phenoxy]methyl]benzonitrile;
CAS Number	73815-11-9 ;
PubChem CID	52542;
ChemSpider	47493 ;
UNII	V6FT1QJ7VL;
KEGG	D02581 ;
ChEMBL	ChEMBL2104092 ;
CompTox Dashboard (EPA)	DTXSID50868273 ;
ECHA InfoCard	100.070.537
Chemical and physical data
Formula	C19H18N2O4
Molar mass	338.363 g·mol−1
	InChI InChI=1S/C19H18N2O4/c1-23-13-18-11-21(19(22)25-18)16-5-7-17(8-6-16)24-12-15-4-2-3-14(9-15)10-20/h2-9,18H,11-13H2,1H3 ; Key:MVVJINIUPYKZHR-UHFFFAOYSA-N ;
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Cimoxatone (MD 780515) is a reversible inhibitor of MAO-A (RIMA).^[1] It has a significant food interaction–related adverse effect in combination with tyramine.^[2] It was never marketed.

References

^ Nair NP, Ahmed SK, Kin NM, West TE (1995). "Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients". Acta Psychiatr Scand Suppl. 386: 28–35. doi:10.1111/j.1600-0447.1995.tb05921.x. PMID 7717092. S2CID 9100689.
^ Nair NP, Ahmed SK, Kin NM (November 1993). "Biochemistry and pharmacology of reversible inhibitors of MAO-A agents: focus on moclobemide". J Psychiatry Neurosci. 18 (5): 214–25. PMC 1188542. PMID 7905288.

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[pmid7717092-1] Nair NP, Ahmed SK, Kin NM, West TE (1995). "Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients". Acta Psychiatr Scand Suppl. 386: 28–35. doi:10.1111/j.1600-0447.1995.tb05921.x. PMID 7717092. S2CID 9100689.

[pmid7905288-2] Nair NP, Ahmed SK, Kin NM (November 1993). "Biochemistry and pharmacology of reversible inhibitors of MAO-A agents: focus on moclobemide". J Psychiatry Neurosci. 18 (5): 214–25. PMC 1188542. PMID 7905288.

[1]

[2]

See also

References