Geraldine Hamilton

Methods And Uses For Ex Vivo Tissue Culture Systems

Application

#2014018 Jul 3, 2014

Filed

May 31, 2012

Inventor

Donald E. Ingber (Boston, MA) · Yusuke Torisawa (Kyoto, JP) · Geraldine Hamilton (Cambridge, MA) · Akiko Mammoto (Brookline, MA) · Tadanori Mammoto (Brookline, MA) · Catherine Spina (Boston, MA)

Appl. No.

14/122273

Assignee

CHILDREN'S MEDICAL CENTER CORPORATION (Boston, MA) · PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, MA)

International Classification

C12N 5/077

U.S. Classification

424422, 435 12, 424 937, 435 2

Abstract

The technology described herein is directed to methods and devices that can be used to induce functional organ structures to form within an implantation device by implanting it in vivo within the...

Removing Bubbles In Microfluidic Systems

Application

#2015020 Jul 30, 2015

Filed

Sep 4, 2013

Inventor

Geraldine A. Hamilton (Cambridge, MA) · Daniel Levner (Boston, MA) · Christopher Hinojosa (Cambridge, MA) · Daniel Patterson (Somerville, MA)

Appl. No.

14/424195

Assignee

President and Fellows of Harvard College (Cambridge, MA)

International Classification

B01L 3/00, B01D 19/00, C12M 1/107, C12M 3/06, C12M 1/04

Abstract

A microfluidic system includes a microfluidic device connected to a bubble trap device whereby fluid flowing to the microfluidic device passes through the bubble trap device to remove gas bubbles...

Organomimetic Devices And Methods Of Use And Manufacturing Thereof

Application

#2016032 Nov 10, 2016

Filed

Dec 19, 2014

Inventor

Norman WEN (Newton, MA) · Richard NOVAK (Jamaica Plain, MA) · Geraldine A. Hamilton (Cambridge, MA) · Christopher Hinojosa (Cambridge, MA) · Karel Domansky (Charlestown, MA) · Daniel Levner (Cambridge, MA) · Guy Thompson, II (Lexington, MA) · Kambez Hajipouran Benam (Cambridge, MA) · Remi Villenave (Boston, MA) · Thomas Umundum (Salzburg, AT) · Alfred Paris (Salzburg, AT) · Georg Bauer (Salzburg, AT)

Appl. No.

15/105388

Assignee

Norman WEN (Newton, MA) · Richard NOVAK (Jamaica Plain, MA) · Geraldine A. Hamilton (Cambridge, MA) · Christopher Hinojosa (Cambridge, MA) · Karel Domansky (Charlestown, MA) · Daniel Levner (Cambridge, MA) · Guy Thompson, II (Lexington, MA) · Kambez Hajipouran Benam (Cambridge, MA) · Remi Villenave (Boston, MA) · Thomas Umundum (Salzburg, AT) · Alfred Paris (Salzburg, AT) · Georg Bauer (Salzburg, AT)

International Classification

C12M 3/06, C12M 1/12, C12M 1/00, C12M 1/42, C12M 1/34

Abstract

An organomimetic device includes a microfluidic device that can be used to culture cells in its microfluidic channels. The organomimetic device can be part of dynamic system that can apply mechanical ...

Additive Channels

Application

#2018001 Jan 18, 2018

Filed

Jul 12, 2017

Inventor

Norman Wen (West Roxbury, MA) · Jacob Fraser (Somerville, MA) · Justin Nguyen (Medford, MA) · Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Hyoung Shin Park (Newton, MA) · Antonio Varone (West Roxbury, MA) · Andries Van der Meer (Enchede, NL) · Monica Otieno (Robbinville, NJ) · David Conegliano (Boston, MA)

Appl. No.

15/648000

Assignee

Norman Wen (West Roxbury, MA) · Jacob Fraser (Somerville, MA) · Justin Nguyen (Medford, MA) · Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Hyoung Shin Park (Newton, MA) · Antonio Varone (West Roxbury, MA) · Andries Van der Meer (Enchede, NL) · Monica Otieno (Robbinville, NJ) · David Conegliano (Boston, MA)

International Classification

G01N 33/86, B01L 3/00

Abstract

Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or...

Additive Channels

Application

#2018001 Jan 18, 2018

Filed

Jul 12, 2017

Inventor

Norman Wen (West Roxbury, MA) · Jacob Fraser (Somerville, MA) · Justin Nguyen (Medford, MA) · Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Hyoung Shin Park (Newton, MA) · Antonio Varone (West Roxbury, MA) · Andries Va der Meer (Enchede, NL) · Monica Otieno (Robbinville, NJ) · David Conegliano (Boston, MA)

Appl. No.

15/648182

Assignee

Norman Wen (West Roxbury, MA) · Jacob Fraser (Somerville, MA) · Justin Nguyen (Medford, MA) · Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Hyoung Shin Park (Newton, MA) · Antonio Varone (West Roxbury, MA) · Andries Va der Meer (Enchede, NL) · Monica Otieno (Robbinville, NJ) · David Conegliano (Boston, MA)

International Classification

G01N 33/86, B01L 3/00

Abstract

Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or...

In Vitro Epithelial Models Comprising Lamina Propria-Derived Cells

Application

#2018018 Jul 5, 2018

Filed

Nov 21, 2017

Inventor

Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Daniel Levner (Brookline, MA) · Carolina Lucchesi (Westwood, MA) · Antonio Varone (West Roxbury, MA) · Remi Villenave (Boston, MA)

Appl. No.

15/819435

Assignee

Riccardo Barrile (Boston, MA) · Geraldine Hamilton (Boston, MA) · Catherine Karalis (Brookline, MA) · Daniel Levner (Brookline, MA) · Carolina Lucchesi (Westwood, MA) · Antonio Varone (West Roxbury, MA) · Remi Villenave (Boston, MA)

International Classification

B01L 3/00, G01N 33/50

Abstract

An in vitro microfluidic “organ-on-chip” is described herein that mimics the structure and at least one function of specific areas of the epithelial system in vivo. In particular, a multicellular,...