iBet uBet web content aggregator. Adding the entire web to your favor.
iBet uBet web content aggregator. Adding the entire web to your favor.



Link to original content: http://pubmed.ncbi.nlm.nih.gov/39240976/
Small for gestational age and age at menarche in a contemporary population-based U.S. sample - PubMed Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Sep 6;19(9):e0309363.
doi: 10.1371/journal.pone.0309363. eCollection 2024.

Small for gestational age and age at menarche in a contemporary population-based U.S. sample

Sruchika Sabu  1 , Hope Corman  2 , Kelly Noonan  3 , Nancy E Reichman  1   4 , Kirsten B Kuhn  5 , Sally Radovick  1
Affiliations

Small for gestational age and age at menarche in a contemporary population-based U.S. sample

Sruchika Sabu et al. PLoS One. .

Abstract

Children born small for gestational age (SGA) may be at risk for earlier puberty and adverse long-term health sequelae. This study investigates associations between SGA and age at menarche using secondary data on 1,027 female children in a population-based U.S. birth cohort that over-sampled non-marital births, which in the U.S. is a policy-relevant population. SGA was defined as <10th percentile of weight for gestational age compared to the national U.S. distribution. We estimated unadjusted and adjusted Ordinary Least Squares (OLS) models of associations between SGA and age at menarche in years, as well as unadjusted and adjusted logistic regression models of associations between SGA and early menarche (before age 11). SGA was not significantly associated with earlier age at menarche, even when adjusting for maternal sociodemographic characteristics, prenatal smoking, and maternal pre-pregnancy overweight and obesity. Similarly, SGA was not significantly associated with the odds of menarche occurring before age 11. However, maternal non-Hispanic Black race-ethnicity, Hispanic ethnicity, and pre-pregnancy obesity all had independent associations with average earlier age at menarche and menarche before age 11. Thus, maternal risk factors appear to play more influential roles in determining pubertal development.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Derivation of analysis sample.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Papadimitriou A. The evolution of the age at menarche from prehistorical to modern times. J Pediatr Adolesc Gynecol. 2016;29(6):527–530. doi: 10.1016/j.jpag.2015.12.002 - DOI - PubMed
    1. Martinez GM. National Health Statistics Reports [Internet]. CDC.gov. 2010. [Cited 2024 July 20]. www.cdc.gov/nchs/data/nhsr/nhsr146-508.pdf.
    1. Seo MY, Kim SH, Juul A, Park MJ. Trend of menarcheal age among Korean girls. J Korean Med Sci. 2020;35(49):e406. doi: 10.3346/jkms.2020.35.e406 - DOI - PMC - PubMed
    1. Kota AS, Sehar Ejaz. Precocious Puberty [Internet]. Nih.gov. StatPearls Publishing; 2019. [Cited 2024 July 20]. https://www.ncbi.nlm.nih.gov/books/NBK544313/. - PubMed
    1. Mishra GD, Nirmala P, Dobson AJ, Chung HF, Anderson D, Kuh D et al.. Early menarche, nulliparity, and the risk for premature and early natural menopause. Hum Reprod. 2017;32(3):679–686. doi: 10.1093/humrep/dew350 - DOI - PMC - PubMed

Grants and funding

Support for this research was provided by award UL1TR003017 from the National Center for Advancing Translational Sciences, a component of the National Institutes of Health and grant 74260 from the Robert Wood Johnson Foundation through its support of the Child Health Institute of New Jersey. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

LinkOut - more resources