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Link to original content: http://pubmed.ncbi.nlm.nih.gov/34975137/
Clinical profile and role of C-reactive protein and lactate dehydrogenase as prognostic marker and comparative efficacy of different pharmacotherapeutic agents in patients with cerebrovascular accident: An observational study - PubMed Skip to main page content
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Observational Study
. 2021 Nov-Dec;53(6):484-488.
doi: 10.4103/ijp.ijp_515_21.

Clinical profile and role of C-reactive protein and lactate dehydrogenase as prognostic marker and comparative efficacy of different pharmacotherapeutic agents in patients with cerebrovascular accident: An observational study

Dibya Jyoti Sharma  1 , K Jeenaleima Singha  1 , Karuna Das  2 , Chandrama Das  1 , M Rakesh  1
Affiliations
Observational Study

Clinical profile and role of C-reactive protein and lactate dehydrogenase as prognostic marker and comparative efficacy of different pharmacotherapeutic agents in patients with cerebrovascular accident: An observational study

Dibya Jyoti Sharma et al. Indian J Pharmacol. 2021 Nov-Dec.

Abstract

The current study was conducted to determine the role of C-reactive protein (CRP) and lactate dehydrogenase (LDH) as prognostic-marker and outcomes of different pharmacotherapeutic agents among patients with cerebrovascular accident (CVA). A hospital-based observational study was conducted and patients with CVA admitted were included. Serum-CRP on admission correlated positively with modified Rankin score (mRS) (r = 0.9, P < 0.001) in ischemic stroke, whereas no correlation between serum LDH with mRS (r = 0.1, P = 0.5) was observed. Neither CRP nor LDH was helpful in predicting the outcome in hemorrhagic stroke. The use of Vitamin B12 was associated with favorable outcome in ischemic CVA cases and use of folic acid was associated with favorable outcome among hemorrhagic-CVA patients.

Keywords: Acute phase substance; C-reactive protein; cerebrovascular accident; lactate dehydrogenase; prognostic marker.

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