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Link to original content: http://pubmed.ncbi.nlm.nih.gov/30943960/
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. 2019 Apr 4;19(Suppl 3):71.
doi: 10.1186/s12911-019-0781-4.

Clinical text classification with rule-based features and knowledge-guided convolutional neural networks

Liang Yao  1 , Chengsheng Mao  1 , Yuan Luo  2
Affiliations

Clinical text classification with rule-based features and knowledge-guided convolutional neural networks

Liang Yao et al. BMC Med Inform Decis Mak. .

Abstract

Background: Clinical text classification is an fundamental problem in medical natural language processing. Existing studies have cocnventionally focused on rules or knowledge sources-based feature engineering, but only a limited number of studies have exploited effective representation learning capability of deep learning methods.

Methods: In this study, we propose a new approach which combines rule-based features and knowledge-guided deep learning models for effective disease classification. Critical Steps of our method include recognizing trigger phrases, predicting classes with very few examples using trigger phrases and training a convolutional neural network (CNN) with word embeddings and Unified Medical Language System (UMLS) entity embeddings.

Results: We evaluated our method on the 2008 Integrating Informatics with Biology and the Bedside (i2b2) obesity challenge. The results demonstrate that our method outperforms the state-of-the-art methods.

Conclusion: We showed that CNN model is powerful for learning effective hidden features, and CUIs embeddings are helpful for building clinical text representations. This shows integrating domain knowledge into CNN models is promising.

Keywords: Clinical text classification; Convolutional neural networks; Entity embeddings; Obesity challenge; Word embeddings.

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Figures

Fig. 1
Fig. 1
The test phase of our method
Fig. 2
Fig. 2
Our knowledge-guided convolutional neural network architecture
See this image and copyright information in PMC

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