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Link to original content: http://pubmed.ncbi.nlm.nih.gov/30643505/
Risk factors and short and medium-term survival after open and endovascular repair of abdominal aortic aneurysms - PubMed Skip to main page content
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. 2018 Jul-Sep;17(3):201-207.
doi: 10.1590/1677-5449.011717.

Risk factors and short and medium-term survival after open and endovascular repair of abdominal aortic aneurysms

Affiliations

Risk factors and short and medium-term survival after open and endovascular repair of abdominal aortic aneurysms

Seleno Glauber de Jesus-Silva et al. J Vasc Bras. 2018 Jul-Sep.

Abstract

Background: Infrarenal abdominal aortic aneurysms (AAA) are responsible for high rates of rupture-associated morbidity and mortality and can be treated by open or endovascular surgery.

Objectives: To analyze risk factors and survival associated with surgical and endovascular AAA treatment methods.

Methods: A retrospective, longitudinal study involving 41 patients who underwent endovascular or open AAA repair, whether elective or emergency, over a 48-month period, with analysis of preoperative comorbidities, 30-day and 1-year survival, in-hospital mortality, length of hospital stay, transfusion of blood products, duration of surgery, and development of acute kidney failure. Inferential statistics and survival analysis considered a 95% CI and p < 0.05 as significant.

Results: Twelve of the 41 patients were treated with open surgery and 29 with endovascular techniques. The majority were male (75%), with an average age of 71 (range: 56 - 90 years). There were no differences in demographic or risk factors between the groups. Overall survival rates for open and endovascular repair were different for both 30 days (37 vs. 72%, p = 0.01) and 360 days (37 vs. 67%, p = 0.01). However, survival rates in elective cases were similar at 30 days (71 vs. 76%, p = 0.44) and 360 days (both 71%, p = 0.34). Endovascular repair showed shorter length of hospital stay (3.0 vs. 4.4 days; p = 0.02) and duration of surgery (111 vs. 163 min; p < 0.01) compared to open repair.

Conclusions: There was no difference in short- or medium-term survival of AAA patients treated electively with endovascular or open surgery. Hospital stays and duration of surgery were both shorter with minimally invasive treatment.

Contexto: Os aneurismas de aorta abdominal (AAA) infrarrenal apresentam alta morbimortalidade associada à ruptura e podem ser tratados por cirurgia aberta ou endovascular.

Objetivos: Analisar os fatores de risco e a sobrevida associados aos métodos cirúrgico e endovascular no tratamento do AAA.

Métodos: Estudo retrospectivo e longitudinal envolvendo 41 pacientes submetidos à correção endovascular ou aberta do AAA, de forma eletiva ou emergencial, no período de 48 meses. Foi realizada análise de comorbidades pré-operatórias, sobrevida em 30 dias e 1 ano, mortalidade hospitalar, tempo de internação, hemotransfusões, duração da cirurgia e ocorrência de insuficiência renal aguda. A estatística inferencial e a análise de sobrevida foram realizadas considerando intervalo de confiança de 95% e p < 0,05 como significante.

Resultados: Dos 41 pacientes, 12 foram submetidos à correção aberta e 29, à endovascular. A maioria eram homens (75%), com média de idade de 71 anos (mín. 56, máx. 90 anos). Não houve diferenças de fatores de risco entre os grupos. A sobrevida global dos pacientes foi diferente para os tratamentos aberto e endovascular, tanto em 30 dias (37 vs. 72%; p = 0,01) quanto em 360 dias (37 vs. 67%; p = 0,01), respectivamente. A sobrevida dos casos eletivos em 30 dias (71 vs. 76%; p = 0,44) e 360 dias (ambas 71%; p = 0,34) foram semelhantes. O reparo endovascular apresentou menor tempo de internação (3,0 vs. 4,4 dias; p = 0,02) e duração da cirurgia (111 vs. 163 min; p = 0,005) quando comparado à cirurgia aberta.

Conclusões: Não houve diferença na sobrevida em curto e médio prazo dos pacientes com AAA tratados de forma eletiva pelas técnicas endovascular e cirúrgica. Menor tempo de internação e duração da cirurgia foram observados no tratamento minimamente invasivo.

Keywords: abdominal aortic aneurysm; blood vessel prosthesis implantation; risk factors; survival analysis.

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Conflict of interest statement

Conflicts of interest: No conflicts of interest declared concerning the publication of this article.

Figures

Figure 1
Figure 1. Kaplan-Meier survival curves with log-rank test for patients treated. In a and b, the global survival curves for all patients (elective and emergency) for 30 and 360 days show significant differences between groups. In c and d, showing an analysis of elective patients only, there is no difference in survival related to the treatment technique chosen.
Figura 1
Figura 1. Curvas de sobrevida de Kaplan-Meier com teste log-rank para os pacientes tratados. Em a e b, a curva de sobrevida global para todos os pacientes (eletivos e urgentes), para 30 e 360 dias, evidencia diferença significativa entre os grupos. Em c e d, a análise isolada dos pacientes eletivos não aponta diferença de sobrevida relacionada à técnica de tratamento empregada.

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