Risk factors and short and medium-term survival after open and endovascular repair of abdominal aortic aneurysms
- PMID: 30643505
- PMCID: PMC6326136
- DOI: 10.1590/1677-5449.011717
Risk factors and short and medium-term survival after open and endovascular repair of abdominal aortic aneurysms
Abstract
Background: Infrarenal abdominal aortic aneurysms (AAA) are responsible for high rates of rupture-associated morbidity and mortality and can be treated by open or endovascular surgery.
Objectives: To analyze risk factors and survival associated with surgical and endovascular AAA treatment methods.
Methods: A retrospective, longitudinal study involving 41 patients who underwent endovascular or open AAA repair, whether elective or emergency, over a 48-month period, with analysis of preoperative comorbidities, 30-day and 1-year survival, in-hospital mortality, length of hospital stay, transfusion of blood products, duration of surgery, and development of acute kidney failure. Inferential statistics and survival analysis considered a 95% CI and p < 0.05 as significant.
Results: Twelve of the 41 patients were treated with open surgery and 29 with endovascular techniques. The majority were male (75%), with an average age of 71 (range: 56 - 90 years). There were no differences in demographic or risk factors between the groups. Overall survival rates for open and endovascular repair were different for both 30 days (37 vs. 72%, p = 0.01) and 360 days (37 vs. 67%, p = 0.01). However, survival rates in elective cases were similar at 30 days (71 vs. 76%, p = 0.44) and 360 days (both 71%, p = 0.34). Endovascular repair showed shorter length of hospital stay (3.0 vs. 4.4 days; p = 0.02) and duration of surgery (111 vs. 163 min; p < 0.01) compared to open repair.
Conclusions: There was no difference in short- or medium-term survival of AAA patients treated electively with endovascular or open surgery. Hospital stays and duration of surgery were both shorter with minimally invasive treatment.
Contexto: Os aneurismas de aorta abdominal (AAA) infrarrenal apresentam alta morbimortalidade associada à ruptura e podem ser tratados por cirurgia aberta ou endovascular.
Objetivos: Analisar os fatores de risco e a sobrevida associados aos métodos cirúrgico e endovascular no tratamento do AAA.
Métodos: Estudo retrospectivo e longitudinal envolvendo 41 pacientes submetidos à correção endovascular ou aberta do AAA, de forma eletiva ou emergencial, no período de 48 meses. Foi realizada análise de comorbidades pré-operatórias, sobrevida em 30 dias e 1 ano, mortalidade hospitalar, tempo de internação, hemotransfusões, duração da cirurgia e ocorrência de insuficiência renal aguda. A estatística inferencial e a análise de sobrevida foram realizadas considerando intervalo de confiança de 95% e p < 0,05 como significante.
Resultados: Dos 41 pacientes, 12 foram submetidos à correção aberta e 29, à endovascular. A maioria eram homens (75%), com média de idade de 71 anos (mín. 56, máx. 90 anos). Não houve diferenças de fatores de risco entre os grupos. A sobrevida global dos pacientes foi diferente para os tratamentos aberto e endovascular, tanto em 30 dias (37 vs. 72%; p = 0,01) quanto em 360 dias (37 vs. 67%; p = 0,01), respectivamente. A sobrevida dos casos eletivos em 30 dias (71 vs. 76%; p = 0,44) e 360 dias (ambas 71%; p = 0,34) foram semelhantes. O reparo endovascular apresentou menor tempo de internação (3,0 vs. 4,4 dias; p = 0,02) e duração da cirurgia (111 vs. 163 min; p = 0,005) quando comparado à cirurgia aberta.
Conclusões: Não houve diferença na sobrevida em curto e médio prazo dos pacientes com AAA tratados de forma eletiva pelas técnicas endovascular e cirúrgica. Menor tempo de internação e duração da cirurgia foram observados no tratamento minimamente invasivo.
Keywords: abdominal aortic aneurysm; blood vessel prosthesis implantation; risk factors; survival analysis.
Conflict of interest statement
Conflicts of interest: No conflicts of interest declared concerning the publication of this article.
Figures
Similar articles
-
Endovascular repair of abdominal aortic aneurysm: an evidence-based analysis.Ont Health Technol Assess Ser. 2002;2(1):1-46. Epub 2002 Mar 1. Ont Health Technol Assess Ser. 2002. PMID: 23074438 Free PMC article.
-
Fenestrated endovascular aneurysm repair is associated with lower perioperative morbidity and mortality compared with open repair for complex abdominal aortic aneurysms.J Vasc Surg. 2019 Jun;69(6):1670-1678. doi: 10.1016/j.jvs.2018.08.192. Epub 2018 Dec 13. J Vasc Surg. 2019. PMID: 30553730
-
Women derive less benefit from elective endovascular aneurysm repair than men.J Vasc Surg. 2012 Apr;55(4):906-13. doi: 10.1016/j.jvs.2011.11.047. Epub 2012 Feb 8. J Vasc Surg. 2012. PMID: 22322123
-
Open versus endovascular stent graft repair of abdominal aortic aneurysms: a meta-analysis of randomized trials.JACC Cardiovasc Interv. 2012 Oct;5(10):1071-80. doi: 10.1016/j.jcin.2012.06.015. JACC Cardiovasc Interv. 2012. PMID: 23078738 Review.
-
Is endovascular repair of ruptured abdominal aortic aneurysms associated with improved in-hospital mortality compared with surgical repair?Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):135-9. doi: 10.1093/icvts/ivu329. Epub 2014 Oct 3. Interact Cardiovasc Thorac Surg. 2015. PMID: 25281705 Review.
Cited by
-
Abdominal aortic aneurysm in prostate cancer patients: the "road map" from incidental detection to advanced predictive, preventive, and personalized approach utilizing common follow-up for both pathologies.EPMA J. 2019 Nov 26;10(4):415-423. doi: 10.1007/s13167-019-00193-y. eCollection 2019 Dec. EPMA J. 2019. PMID: 31832115 Free PMC article.
-
Blood biomarker panel recommended for personalized prediction, prognosis, and prevention of complications associated with abdominal aortic aneurysm.EPMA J. 2019 Jun 3;10(2):125-135. doi: 10.1007/s13167-019-00173-2. eCollection 2019 Jun. EPMA J. 2019. PMID: 31258818 Free PMC article.
References
-
- Novero ER, Metzger PB, Angelieri F, et al. Correção endovascular do aneurisma da aorta abdominal: análise dos resultados de único centro. Radiol Bras. 2012;45(1):1–6. doi: 10.1590/S0100-39842012000100003. - DOI
LinkOut - more resources
Full Text Sources