Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017

doi:10.1089/AID.2017.0310

. 2018 Jul;34(7):561-569.

doi: 10.1089/AID.2017.0310. Epub 2018 Jun 5.

Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017

R Clive Landis^{1

2}, E Akinola Abayomi³, Brendan C Bain⁴, Edward Greene⁵, George Janossy⁶, Patrice Joseph⁷, Deanna Kerrigan⁸, J Philip McCoy⁹, Cesar Nunez¹⁰, Maurice O'Gorman¹¹, Alexander Pastoors¹², Bharat S Parekh¹³, Kim R Quimby¹, Thomas C Quinn¹⁴, Kevin R Robertson¹⁵, Réjean Thomas¹⁶, Eric van Gorp¹⁷, Sten H Vermund¹⁸, Valerie Wilson¹⁹

Affiliations

¹ 1 Edmund Cohen Laboratory for Vascular Research, George Alleyne Chronic Disease Research Centre, The University of the West Indies , Bridgetown, Barbados .
² 2 Office of the Deputy Principal, The University of the West Indies - Cave Hill Campus , Bridgetown, Barbados .
³ 3 Division of Haematopathology, Faculty of Medicine, Tygerberg Academic Hospital, Stellenbosch University , Cape Town, South Africa .
⁴ 4 Department of Medicine, University Hospital of the West Indies , Mona, Jamaica .
⁵ 5 Office of the UN Secretary General , United Nations, New York, New York.
⁶ 6 Department of Immunology, University College Medical School, University College , London, United Kingdom .
⁷ 7 Groupe Haïtien Etude pour le Sarcome de Kaposi et les Infections Opportunistes (GHESKIO) , Port-au-Prince, Haiti .
⁸ 8 Department of Health, Behavior and Society, The Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland.
⁹ 9 National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda, Maryland.
¹⁰ 10 UNAIDS Latin American and Caribbean Regional Support Team , Panama City, Panama .
¹¹ 11 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California , Los Angeles, California.
¹² 12 Dutch Association of PLHIV , Amsterdam, the Netherlands .
¹³ 13 Division of Global HIV and TB, Centers for Disease Control and Prevention , Atlanta, Georgia .
¹⁴ 14 National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
¹⁵ 15 Department of Neurology, University of North Carolina , Chapel Hill, North Carolina.
¹⁶ 16 Clinique médicale l'Actuel , Montreal, Canada .
¹⁷ 17 Department of Viroscience, Erasmus Medical Centre , Rotterdam, the Netherlands .
¹⁸ 18 Yale School of Public Health , New Haven, Connecticut.
¹⁹ 19 Caribbean Med Labs Foundation , Port of Spain , Trinidad.

PMID: 29732897
PMCID: PMC6053839
DOI: 10.1089/AID.2017.0310

Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017

R Clive Landis et al. AIDS Res Hum Retroviruses. 2018 Jul.

. 2018 Jul;34(7):561-569.

doi: 10.1089/AID.2017.0310. Epub 2018 Jun 5.

Authors

Affiliations

¹ 1 Edmund Cohen Laboratory for Vascular Research, George Alleyne Chronic Disease Research Centre, The University of the West Indies , Bridgetown, Barbados .
² 2 Office of the Deputy Principal, The University of the West Indies - Cave Hill Campus , Bridgetown, Barbados .
³ 3 Division of Haematopathology, Faculty of Medicine, Tygerberg Academic Hospital, Stellenbosch University , Cape Town, South Africa .
⁴ 4 Department of Medicine, University Hospital of the West Indies , Mona, Jamaica .
⁵ 5 Office of the UN Secretary General , United Nations, New York, New York.
⁶ 6 Department of Immunology, University College Medical School, University College , London, United Kingdom .
⁷ 7 Groupe Haïtien Etude pour le Sarcome de Kaposi et les Infections Opportunistes (GHESKIO) , Port-au-Prince, Haiti .
⁸ 8 Department of Health, Behavior and Society, The Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland.
⁹ 9 National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda, Maryland.
¹⁰ 10 UNAIDS Latin American and Caribbean Regional Support Team , Panama City, Panama .
¹¹ 11 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California , Los Angeles, California.
¹² 12 Dutch Association of PLHIV , Amsterdam, the Netherlands .
¹³ 13 Division of Global HIV and TB, Centers for Disease Control and Prevention , Atlanta, Georgia .
¹⁴ 14 National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
¹⁵ 15 Department of Neurology, University of North Carolina , Chapel Hill, North Carolina.
¹⁶ 16 Clinique médicale l'Actuel , Montreal, Canada .
¹⁷ 17 Department of Viroscience, Erasmus Medical Centre , Rotterdam, the Netherlands .
¹⁸ 18 Yale School of Public Health , New Haven, Connecticut.
¹⁹ 19 Caribbean Med Labs Foundation , Port of Spain , Trinidad.

PMID: 29732897
PMCID: PMC6053839
DOI: 10.1089/AID.2017.0310

Abstract

The CCAS EXPERT SUMMIT convened an array of international experts in Barbados on August 27-31, 2017 under the theme "From Care to Cure-Shifting the HIV Paradigm." The Caribbean Cytometry & Analytical Society (CCAS) partnered with the Joint United Nations Programme on HIV/AIDS (UNAIDS) to deliver a program that reviewed the advances in antiretroviral therapy and the public health benefits accruing from treatment as prevention. Particular emphasis was placed on reexamining stigma and discrimination through a critical appraisal of whether public health messaging and advocacy had kept pace with the advances in medicine. Persistent fear of HIV driving discriminatory behavior was widely reported in different regions and sectors, including the healthcare profession itself; continued fear of the disease was starkly misaligned with the successes of new medical treatments and progress toward the UNAIDS 90-90-90 targets. The summit therefore adopted the mantra "Test-Treat-Defeat" to help engage with the public in a spirit of optimism aimed at creating a more conducive environment for persons to be tested and treated and, thereby, help reduce HIV disease and stigma at the individual and community levels.

Keywords: HIV; cure; monitoring; prevention; stigma; treatment.

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Conflict of interest statement

Dr. Landis as Chairman of The CCAS discloses having received funds from the following sponsoring companies to host the Caribbean Expert Summit “From Care to Cure: Shifting the HIV Paradigm”: Alere, BD Biosciences, Beckman Coulter, Hologic, Roche Diagnostics, Ryvex, and Sysmex. Dr. Bharat Parekh discloses that as an inventor of Rapid Recency Assay he receives a portion of royalties from the sale of Rapid Recency Assay, as per policy of U.S. Government.

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References

1. Mandy FF, Bergeron M, Minkus T: Evolution of leukocyte immunophenotyping as influenced by the HIV/AIDS pandemic: A short history of the development of gating strategies for CD4+ T-cell enumeration. Cytometry 1997;30:157–165 - PubMed
1. Tung JW, Heydari K, Tirouvanziam R, et al. : Modern flow cytometry: A practical approach. Clin Lab Med 2007;27:453–468, v - PMC - PubMed
1. Janossy G, Shapiro H: Simplified cytometry for routine monitoring of infectious diseases. Cytometry B Clin Cytom 2008;74 Suppl 1:S6–S10 - PubMed
1. Crisp N: Co-development, innovation and mutual learning—Or how we need to turn the world upside down. Healthc (Amst) 2015;3:221–224 - PubMed
1. Merson M, Denny TN: The global health and diagnostic (flow) cytometry—Breakthroughs in HIV and tuberculosis. Cytometry B Clin Cytom 2008;74 Suppl 1:S4–S5 - PubMed

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[1] Mandy FF, Bergeron M, Minkus T: Evolution of leukocyte immunophenotyping as influenced by the HIV/AIDS pandemic: A short history of the development of gating strategies for CD4+ T-cell enumeration. Cytometry 1997;30:157–165 - PubMed

[2] Mandy FF, Bergeron M, Minkus T: Evolution of leukocyte immunophenotyping as influenced by the HIV/AIDS pandemic: A short history of the development of gating strategies for CD4+ T-cell enumeration. Cytometry 1997;30:157–165 - PubMed

[3] Tung JW, Heydari K, Tirouvanziam R, et al. : Modern flow cytometry: A practical approach. Clin Lab Med 2007;27:453–468, v - PMC - PubMed

[4] Tung JW, Heydari K, Tirouvanziam R, et al. : Modern flow cytometry: A practical approach. Clin Lab Med 2007;27:453–468, v - PMC - PubMed

[5] Janossy G, Shapiro H: Simplified cytometry for routine monitoring of infectious diseases. Cytometry B Clin Cytom 2008;74 Suppl 1:S6–S10 - PubMed

[6] Janossy G, Shapiro H: Simplified cytometry for routine monitoring of infectious diseases. Cytometry B Clin Cytom 2008;74 Suppl 1:S6–S10 - PubMed

[7] Crisp N: Co-development, innovation and mutual learning—Or how we need to turn the world upside down. Healthc (Amst) 2015;3:221–224 - PubMed

[8] Crisp N: Co-development, innovation and mutual learning—Or how we need to turn the world upside down. Healthc (Amst) 2015;3:221–224 - PubMed

[9] Merson M, Denny TN: The global health and diagnostic (flow) cytometry—Breakthroughs in HIV and tuberculosis. Cytometry B Clin Cytom 2008;74 Suppl 1:S4–S5 - PubMed

[10] Merson M, Denny TN: The global health and diagnostic (flow) cytometry—Breakthroughs in HIV and tuberculosis. Cytometry B Clin Cytom 2008;74 Suppl 1:S4–S5 - PubMed

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Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017

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Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017

Authors

Affiliations

Abstract

Conflict of interest statement

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