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Link to original content: http://pubmed.ncbi.nlm.nih.gov/23801528/
Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis - PubMed Skip to main page content
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Review
. 2013 Aug;27(8):591-609.
doi: 10.1007/s40263-013-0080-z.

Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis

Jiwon Oh  1 , Paul W O'Connor
Affiliations
Review

Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis

Jiwon Oh et al. CNS Drugs. 2013 Aug.

Abstract

Treatment options for relapsing-remitting multiple sclerosis (RRMS) have been continuously expanding in recent years, and the emergence of a number of oral disease-modifying agents (DMAs) has significantly changed the landscape of therapeutic options for MS patients. Many of these oral DMAs have demonstrated satisfactory safety and tolerability profiles in clinical trial settings, but the long-term safety of these agents is an important concern. This review discusses salient points on the safety and clinical efficacy of the approved and emerging novel oral therapies in RRMS, including fingolimod, teriflunomide, dimethyl fumarate, laquinimod, and cladribine.

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