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Review
. 2012 Nov;37(5):821-8.
doi: 10.1007/s12038-012-9225-3.

Large SNP arrays for genotyping in crop plants

Martin W Ganal  1 , Andreas Polley, Eva-Maria Graner, Joerg Plieske, Ralf Wieseke, Hartmut Luerssen, Gregor Durstewitz
Affiliations
Review

Large SNP arrays for genotyping in crop plants

Martin W Ganal et al. J Biosci. 2012 Nov.

Abstract

Genotyping with large numbers of molecular markers is now an indispensable tool within plant genetics and breeding. Especially through the identification of large numbers of single nucleotide polymorphism (SNP) markers using the novel high-throughput sequencing technologies, it is now possible to reliably identify many thousands of SNPs at many different loci in a given plant genome. For a number of important crop plants, SNP markers are now being used to design genotyping arrays containing thousands of markers spread over the entire genome and to analyse large numbers of samples. In this article, we discuss aspects that should be considered during the design of such large genotyping arrays and the analysis of individuals. The fact that crop plants are also often autopolyploid or allopolyploid is given due consideration. Furthermore, we outline some potential applications of large genotyping arrays including high-density genetic mapping, characterization (fingerprinting) of genetic material and breeding-related aspects such as association studies and genomic selection.

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