doi: 10.1016/S0140-6736(04)17023-2.
Antenatal anthelmintic treatment, birthweight, and infant survival in rural Nepal
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- PMID: 15364190
- DOI: 10.1016/S0140-6736(04)17023-2
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Antenatal anthelmintic treatment, birthweight, and infant survival in rural Nepal
Lancet.
2004 Sep.
Abstract
Anthelmintic treatment, which is recommended during pregnancy in areas where there is a high rate of anaemia, needs further investigation. We examined prospectively the association between anthelmintic treatment and maternal anaemia, birthweight, and infant mortality in a study of prenatal supplements, in which women received albendazole twice during pregnancy. Women given albendazole in the second trimester of pregnancy had a lower rate of severe anaemia during the third trimester. Birthweight of infants of women who had received two doses of albendazole rose by 59 g (95% CI 19-98), and infant mortality at 6 months fell by 41% (RR 0.59; 95% CI 0.43-0.82). Antenatal anthelmintics could be effective in reducing maternal anaemia and improving birthweight and infant survival in hookworm-endemic regions.
Comment in
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Micronutrient supplementation in pregnancy.Lancet. 2005 Dec 10;366(9502):2001-2; author reply 2002-3. doi: 10.1016/S0140-6736(05)67808-7. Lancet. 2005. PMID: 16338443 No abstract available.
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