PROSITE documentation PDOC51222DCD domain profile
The DCD domain is found in plant proteins involved in development and cell death. The DCD domain is an ~130 amino acid long stretch that contains several mostly invariable motifs. These include a FGLP and a LFL motif at the N-terminus and a PAQV and a PLxE motif towards the C-terminus of the domain. The DCD domain is present in proteins with different architectures. Some of these proteins contain additional recognizable motifs, like the KELCH repeats or the ParB domain [1].
The predicted secondary structure of the DCD domain is mostly composed of β strands and confined by an α-helix at the N- and at the C-terminus [1].
some proteins known to contain a DCD domain are listed below:
- Carrot B2 protein.
- Pea Gda-1 protein.
- Soybean N-rich protein (NRP).
The profile we developed covers the entire DCD domain.
Last update:June 2006 / First entry.
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PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Tenhaken R. Doerks T. Bork P. |
| Title | DCD - a novel plant specific domain in proteins involved in development and programmed cell death. | |
| Source | BMC Bioinformatics 6:169-169(2005). | |
| PubMed ID | 16008837 | |
| DOI | 10.1186/1471-2105-6-169 |
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