PROSITE documentation PDOC01015Prolipoprotein diacylglyceryl transferase signature
Description
Prolipoprotein diacylglyceryl transferase [1] is the bacterial enzyme that catalyzes the first step in lipoprotein biogenesis, it transfers the n-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins. Prolipoprotein diacylglyceryl transferase (gene lgt) is an integral membrane protein.
As a signature pattern for this family, we selected a highly conserved region located in the central part of the protein.
Last update:April 2006 / Pattern revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Sankaran K. Wu H.C. |
| Title | Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. | |
| Source | J. Biol. Chem. 269:19701-19706(1994). | |
| PubMed ID | 8051048 |
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