PROSITE documentation PDOC00775Transcription termination factor nusG signature
Description
The nusG protein [1,2] is a bacterial transcriptional elongation factor that NusG protein [1,2] is a bacterial transcriptional elongation factor that component of the transcription complex and interacts with the termination factor rho and RNA polymerase.
NusG is a protein of 177 to 353 amino-acid residues [3,4] whose C-terminal sequence is well conserved. We developed a signature pattern from the most conserved part of nusG.
Last update:November 1997 / Pattern and text revised.
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Technical section
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References
| 1 | Authors | Li J. Horwitz R. McCracken S. Greenblatt J. |
| Title | NusG, a new Escherichia coli elongation factor involved in transcriptional antitermination by the N protein of phage lambda. | |
| Source | J. Biol. Chem. 267:6012-6019(1992). | |
| PubMed ID | 1532577 |
| 2 | Authors | Li J. Mason S.W. Greenblatt J. |
| Title | Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription. | |
| Source | Genes Dev. 7:161-172(1993). | |
| PubMed ID | 8422985 |
| 3 | Authors | Heinrich T. Schroder W. Erdmann V.A. Hartmann R.K. |
| Title | Identification of the gene encoding transcription factor NusG of Thermus thermophilus. | |
| Source | J. Bacteriol. 174:7859-7863(1992). | |
| PubMed ID | 1447157 |
| 4 | Authors | Miyake K. Onaka H. Horinouchi S. Beppu T. |
| Title | Organization and nucleotide sequence of the secE-nusG region of Streptomyces griseus. | |
| Source | Biochim. Biophys. Acta 1217:97-100(1994). | |
| PubMed ID | 8286423 |
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